AIMC Topic: Precision Medicine

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Deep Learning in Drug Discovery and Medicine; Scratching the Surface.

Molecules (Basel, Switzerland)
The practice of medicine is ever evolving. Diagnosing disease, which is often the first step in a cure, has seen a sea change from the discerning hands of the neighborhood physician to the use of sophisticated machines to use of information gleaned f...

Development of deep neural network for individualized hepatobiliary toxicity prediction after liver SBRT.

Medical physics
BACKGROUND: Accurate prediction of radiation toxicity of healthy organs-at-risks (OARs) critically determines the radiation therapy (RT) success. The existing dose-volume histogram-based metric may grossly under/overestimate the therapeutic toxicity ...

Digital Diabetes Data and Artificial Intelligence: A Time for Humility Not Hubris.

Journal of diabetes science and technology
In the future artificial intelligence (AI) will have the potential to improve outcomes diabetes care. With the creation of new sensors for physiological monitoring sensors and the introduction of smart insulin pens, novel data relationships based on ...

eDoctor: machine learning and the future of medicine.

Journal of internal medicine
Machine learning (ML) is a burgeoning field of medicine with huge resources being applied to fuse computer science and statistics to medical problems. Proponents of ML extol its ability to deal with large, complex and disparate data, often found with...

Personalized prediction model for seizure-free epilepsy with levetiracetam therapy: a retrospective data analysis using support vector machine.

British journal of clinical pharmacology
AIMS: To predict the probability of a seizure-free (SF) state in patients with epilepsy (PWEs) after treatment with levetiracetam and to identify the clinical and electroencephalographic (EEG) factors that affect outcomes.

Rise of Deep Learning for Genomic, Proteomic, and Metabolomic Data Integration in Precision Medicine.

Omics : a journal of integrative biology
Machine learning (ML) is being ubiquitously incorporated into everyday products such as Internet search, email spam filters, product recommendations, image classification, and speech recognition. New approaches for highly integrated manufacturing and...

Learning for Personalized Medicine: A Comprehensive Review From a Deep Learning Perspective.

IEEE reviews in biomedical engineering
With the recent advancements in analyzing high-volume, complex, and unstructured data, modern learning methods are playing an increasingly critical role in the field of personalized medicine. Personalized medicine (i.e., providing tailored medical tr...

An unsupervised machine learning method for discovering patient clusters based on genetic signatures.

Journal of biomedical informatics
INTRODUCTION: Many chronic disorders have genomic etiology, disease progression, clinical presentation, and response to treatment that vary on a patient-to-patient basis. Such variability creates a need to identify characteristics within patient popu...