AIMC Topic: Prognosis

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Prognostic biomarkers for predicting papillary thyroid carcinoma patients at high risk using nine genes of apoptotic pathway.

PloS one
Aberrant expressions of apoptotic genes have been associated with papillary thyroid carcinoma (PTC) in the past, however, their prognostic role and utility as biomarkers remains poorly understood. In this study, we analysed 505 PTC patients by employ...

Multi-Run Concrete Autoencoder to Identify Prognostic lncRNAs for 12 Cancers.

International journal of molecular sciences
BACKGROUND: Long non-coding RNA plays a vital role in changing the expression profiles of various target genes that lead to cancer development. Thus, identifying prognostic lncRNAs related to different cancers might help in developing cancer therapy.

A priori prediction of local failure in brain metastasis after hypo-fractionated stereotactic radiotherapy using quantitative MRI and machine learning.

Scientific reports
This study investigated the effectiveness of pre-treatment quantitative MRI and clinical features along with machine learning techniques to predict local failure in patients with brain metastasis treated with hypo-fractionated stereotactic radiation ...

Machine Learning for Predicting Motor Improvement After Acute Subcortical Infarction Using Baseline Whole Brain Volumes.

Neurorehabilitation and neural repair
Neuroimaging biomarkers are valuable predictors of motor improvement after stroke, but there is a gap between published evidence and clinical usage. In this work, we aimed to investigate whether machine learning techniques, when applied to a combin...

A Natural Language Processing-Based Approach for Identifying Hospitalizations for Worsening Heart Failure Within an Integrated Health Care Delivery System.

JAMA network open
IMPORTANCE: The current understanding of epidemiological mechanisms and temporal trends in hospitalizations for worsening heart failure (WHF) is based on claims and national reporting databases. However, these data sources are inherently limited by t...

Deep Learning in Cancer Diagnosis and Prognosis Prediction: A Minireview on Challenges, Recent Trends, and Future Directions.

Computational and mathematical methods in medicine
Deep learning (DL) is a branch of machine learning and artificial intelligence that has been applied to many areas in different domains such as health care and drug design. Cancer prognosis estimates the ultimate fate of a cancer subject and provides...

On learning disentangled representations for individual treatment effect estimation.

Journal of biomedical informatics
OBJECTIVE: Estimating the individualized treatment effect (ITE) from observational data is a challenging task due to selection bias, which results from the distributional discrepancy between different treatment groups caused by the dependence between...

A deep learning- and CT image-based prognostic model for the prediction of survival in non-small cell lung cancer.

Medical physics
OBJECTIVE: To assist clinicians in arranging personalized treatment, planning follow-up programs and extending survival times for non-small cell lung cancer (NSCLC) patients, a method of deep learning combined with computed tomography (CT) imaging fo...

Hierarchical graph representations in digital pathology.

Medical image analysis
Cancer diagnosis, prognosis, and therapy response predictions from tissue specimens highly depend on the phenotype and topological distribution of constituting histological entities. Thus, adequate tissue representations for encoding histological ent...