AIMC Topic: Prognosis

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Machine learning-based integration develops relapse related signature for predicting prognosis and indicating immune microenvironment infiltration in breast cancer.

Scientific reports
Breast cancer is the most common type of cancer in women, and while current treatments can cure the majority of early-stage primary BC cases, recurrence remains a significant challenge. Traditional methods of assessing patient prognosis, such as AJCC...

Machine learning-based prediction model for cognitive impairment risk in patients with chronic kidney disease.

PloS one
BACKGROUND: The high prevalence of cognitive impairment (CI) in Chronic kidney disease (CKD) patients impacts their quality of life and prognosis, yet risk prediction models for CI in this population remain underexplored.

Predicting clinical prognosis in gastric cancer using deep learning-based analysis of tissue pathomics images.

Computer methods and programs in biomedicine
OBJECTIVE: Evaluate the utility of a machine learning-based pathomics model in predicting overall survival (OS) post-surgery for gastric cancer patients.

Predicting clinical outcomes using 18F-FDG PET/CT-based radiomic features and machine learning algorithms in patients with esophageal cancer.

Nuclear medicine communications
OBJECTIVE: This study evaluated the relationship between 18F-fluorodeoxyglucose PET/computed tomography (18F-FDG PET/CT) radiomic features and clinical parameters, including tumor localization, histopathological subtype, lymph node metastasis, mortal...

Machine learning-based histopathological features of histological slides and clinical characteristics as a novel prognostic indicator in diffuse large B-cell lymphoma.

Pathology, research and practice
OBJECTIVE: This study developed and validated a deep learning model based on clinical and histopathological features for predicting the outcomes of diffuse large B-cell lymphoma (DLBCL).

Development of a machine learning-based model to predict urethral recurrence following radical cystectomy: a multicentre retrospective study and updated meta-analysis.

Scientific reports
Urethral recurrence (UR) following radical cystectomy for bladder cancer represents an aggressive disease failure with typically poor survival outcomes. Our study aimed to assess the predictive risk factors for UR, to develop and validate an easy-to-...

Construction and validation of a prognostic nomogram model integrating machine learning-pathomics and clinical features in IDH-wildtype glioblastoma.

Journal of translational medicine
BACKGROUND: Novel diagnostic criteria for glioblastoma (GBM) in the 2021 WHO classification emphasize the importance of integrating pathological and molecular features. Pathomics, which involves the extraction of digital pathology data, is gaining si...

DeepSurv-based deep learning model for survival prediction and personalized treatment recommendation in tongue squamous cell carcinoma.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
We developed a DeepSurv-based deep neural network for survival prediction and treatment recommendation in tongue squamous cell carcinoma (TSCC). The model was trained on 2,015 patients from the Surveillance, Epidemiology, and End Results (SEER) datab...

Machine-learning model for predicting left atrial thrombus in patients with paroxysmal atrial fibrillation.

BMC cardiovascular disorders
OBJECTIVE: Left atrial thrombus (LAT) poses a significant risk for stroke and other thromboembolic complication in patients with atrial fibrillation (AF). This study aimed to evaluate the incidence and predictors of LAT in patients with paroxysmal AF...

Targeting INF2 with DiosMetin 7-O-β-D-Glucuronide: a new stratagem for colorectal cancer therapy.

BMC cancer
BACKGROUND AND PURPOSE: Colorectal cancer (CRC) is the third most prevalent malignancy in the gastrointestinal tract and the second leading cause of cancer-related deaths. Despite the identification of numerous biomarkers, their non-specific distribu...