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Proportional Hazards Models

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Learning Effective Treatment Pathways for Type-2 Diabetes from a clinical data warehouse.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Treatment guidelines for management of type-2 diabetes mellitus (T2DM) are controversial because existing evidence from randomized clinical trials do not address many important clinical questions. Data from Electronic Medical Records (EMRs) has been ...

Non-small cell lung cancer: quantitative phenotypic analysis of CT images as a potential marker of prognosis.

Scientific reports
This was a retrospective study to investigate the predictive and prognostic ability of quantitative computed tomography phenotypic features in patients with non-small cell lung cancer (NSCLC). 661 patients with pathological confirmed as NSCLC were en...

Ileostomy creation in colorectal cancer surgery: risk of acute kidney injury and chronic kidney disease.

The Journal of surgical research
BACKGROUND: Ileostomy creation is associated with postoperative dehydration and readmission; however, the effect on renal function is unknown. Our goal was to characterize the impact of ileostomy creation on acute and chronic renal function.

A Concept-Wide Association Study of Clinical Notes to Discover New Predictors of Kidney Failure.

Clinical journal of the American Society of Nephrology : CJASN
BACKGROUND AND OBJECTIVES: Identifying predictors of kidney disease progression is critical toward the development of strategies to prevent kidney failure. Clinical notes provide a unique opportunity for big data approaches to identify novel risk fac...

Serum Dickkopf-1 levels as a clinical and prognostic factor in patients with bladder cancer.

Genetics and molecular research : GMR
Dickkopf-1 (DKK-1) is a secreted protein that inhibits Wnt signaling. However, the clinical significance and prognostic value of serum DKK-1 levels have not been previously investigated in bladder cancer in Chinese patients. Blood samples were taken ...

Long-Term Oncological and Functional Outcomes of Partial Nephrectomy in Solitary Kidneys.

Clinical genitourinary cancer
BACKGROUND: In this study we assessed the efficacy of nephron-sparing surgery and the changes in renal function after surgery in patients with solitary kidneys.

The relationship of blood transfusion with peri-operative and long-term outcomes after major hepatectomy for metastatic colorectal cancer: a multi-institutional study of 456 patients.

HPB : the official journal of the International Hepato Pancreato Biliary Association
BACKGROUND: Data on prognostic implications of peri-operative blood transfusion around resection of colorectal cancer liver metastases (CRLM) are conflicting. This retrospective study assesses the association of transfusion with complications and dis...