AIMC Topic: Pulmonary Disease, Chronic Obstructive

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ZNF143 as a diagnostic biomarker: Insights from gene expression and immune cell infiltration in COPD and asthma.

Medicine
Chronic obstructive pulmonary disease (COPD) and asthma are common and serious respiratory diseases worldwide. Their clinical overlap and lack of specificity in current biomarkers pose a great diagnostic challenge for early diagnosis. To address this...

Utilizing artificial intelligence and medical experts to identify predictors for common diagnoses in dyspneic adults: A cross-sectional study of consecutive emergency department patients from Southern Sweden.

International journal of medical informatics
OBJECTIVE: Half of all adult emergency department (ED) visits with a complaint of dyspnea involve acute heart failure (AHF), exacerbation of chronic obstructive pulmonary disease (eCOPD), or pneumonia, which are often misdiagnosed. We aimed to create...

Developing a Panel of Shared Susceptibility Genes as Diagnostic Biomarkers for chronic obstructive pulmonary disease and Heart Failure.

Computers in biology and medicine
AIM: Chronic obstructive pulmonary disease (COPD) and heart failure (HF) are closely intertwined comorbidities that present significant clinical challenges due to the poorly understood pathophysiological mechanisms driving their coexistence. In this ...

Oscillometry-defined Small Airway Dysfunction in Tobacco-exposed Adults with Impaired or Preserved Airflow.

American journal of respiratory and critical care medicine
Small airway dysfunction (SAD) is a key feature of chronic obstructive pulmonary disease and might present in tobacco-exposed adults with normal spirometry. So far, the role of oscillometry-defined SAD in this population is largely unexplored. To i...

Time-Aware Tranformer-Based Prediction Model for AECOPD.

Studies in health technology and informatics
The rapid symptom change of Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) makes it critical to have time-sensitive prediction models. However, most current machine learning models studying AECOPD use clinical and laboratory dat...

Development of Multivariable Prediction Models for 30-Day Risk of Readmission After COPD Hospital Admission: A Retrospective Cohort Study Using Electronic Medical Record Data from 7 Hospitals.

Studies in health technology and informatics
BACKGROUND: Approximately 20% of patients who are discharged from hospital for an acute exacerbation of COPD (AECOPD) are readmitted within 30 days. Prediction scores are helpful to identify those who are at higher risk of readmission, such that they...

Integrating single-cell analysis and machine learning to identify COPD hub genes and explore the intervention mechanism of effective component compatibility of Bufei Yishen formula III.

Journal of ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE: Chronic obstructive pulmonary disease (COPD) is a prevalent condition that poses a major threat to public health. Endothelial cells play a critical role in COPD pathogenesis. Recent evidence suggests that the effective...

[Optimizing a standardized management model for chronic obstructive pulmonary disease in primary healthcare institutions].

Zhonghua yi xue za zhi
Chronic obstructive pulmonary disease (COPD) affects nearly 100 million individuals in China and has become a major public health challenge. Primary healthcare institutions serve as the frontline for implementing comprehensive COPD management strateg...

Exploring nanoparticles in lungs under COPD conditions for nanospray drug flow and deposition: CFD simulations and AI predictions.

International journal of pharmaceutics
Chronic obstructive pulmonary disease (COPD) plays a heavy burden on individuals and the social health system, not only causing direct medical costs but also economic losses. Today, treatments for COPD include drugs, bronchodilators, and oxygen thera...

A robust chronic obstructive pulmonary disease classification model using dragonfly optimized kernel extreme learning machine.

Scientific reports
Chronic obstructive pulmonary disease (COPD) is considered to be one of the most commonly occurring respiratory disorders and is proliferating at an extremely high rate in the recent years. The proposed system aims to classify the various stages of C...