AIMC Topic: Quality-Adjusted Life Years

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Artificial neural network metamodel for sensitivity analysis in a total hip replacement health economic model.

Expert review of pharmacoeconomics & outcomes research Sep 13, 2019
: Metamodels have been used to approximate complex simulations and have many applications with sensitivity analysis, optimization, etc. However, their use in health economics is very limited. Application of artificial neural network (ANN) with a heal...
Neural Networks, Computer Humans Computer Simulation Normal Distribution Models, Economic Quality-Adjusted Life Years Linear Models Arthroplasty, Replacement, Hip
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Broadening the Perspective of Cost-Effectiveness Modeling in Chronic Obstructive Pulmonary Disease: A New Patient-Level Simulation Model Suitable to Evaluate Stratified Medicine.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research Dec 20, 2018
OBJECTIVES: To develop a health economic model that included a great diversity of patient characteristics and outcomes for chronic obstructive pulmonary disease (COPD), which can be used to inform decisions about stratified medicine in COPD.
Quality-Adjusted Life Years Male Humans Middle Aged Computer Simulation Cost-Benefit Analysis Female Models, Economic Pulmonary Disease, Chronic Obstructive
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Robot Assisted Training for the Upper Limb after Stroke (RATULS): study protocol for a randomised controlled trial.

Trials Jul 20, 2017
BACKGROUND: Loss of arm function is a common and distressing consequence of stroke. We describe the protocol for a pragmatic, multicentre randomised controlled trial to determine whether robot-assisted training improves upper limb function following ...
Quality of Life Time Factors Treatment Outcome Recovery of Function Stroke Exercise Therapy Cost-Benefit Analysis Robotics Disability Evaluation Humans Research Design Biomechanical Phenomena Health Care Costs Upper Extremity Stroke Rehabilitation Models, Economic Clinical Protocols Quality-Adjusted Life Years United Kingdom State Medicine
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Can Robot-Assisted Unicompartmental Knee Arthroplasty Be Cost-Effective? A Markov Decision Analysis.

The Journal of arthroplasty Oct 26, 2015
BACKGROUND: Unicompartmental knee arthroplasty (UKA) is a treatment option for single-compartment knee osteoarthritis. Robotic assistance may improve survival rates of UKA, but the cost-effectiveness of robot-assisted UKA is unknown. The purpose of t...
Humans Osteoarthritis, Knee Hospitals Markov Chains Robotics Decision Trees Decision Support Techniques Quality-Adjusted Life Years Knee Joint Aged Arthroplasty, Replacement, Knee Cost-Benefit Analysis Survival Rate Reoperation Middle Aged
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Clinical and economic effectiveness of Schroth therapy in adolescent idiopathic scoliosis: insights from a machine learning- and active learning-based real-world study.

Journal of orthopaedic surgery and research May 27, 2025
BACKGROUND: Adolescent idiopathic scoliosis (AIS) is a prevalent musculoskeletal condition affecting approximately 2-3% of the adolescent population. Although exercise-based therapeutic interventions are increasingly employed as non-surgical alternat...
Machine Learning Scoliosis Retrospective Studies Humans Female Male Exercise Therapy Cost-Benefit Analysis Adolescent Quality-Adjusted Life Years Treatment Outcome
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Cost-effectiveness of opportunistic osteoporosis screening using chest radiographs with deep learning in Germany.

Aging clinical and experimental research May 13, 2025
BACKGROUND: Osteoporosis is often underdiagnosed due to limitations in traditional screening methods, leading to missed early intervention opportunities. AI-driven screening using chest radiographs could improve early detection, reduce fracture risk,...
Humans Osteoporosis Female Aged Middle Aged Quality-Adjusted Life Years Deep Learning Germany Mass Screening Radiography, Thoracic Cost-Benefit Analysis Markov Chains
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Protocol for evaluating the cost-effectiveness of Mongolia's sugar-sweetened beverages tax using double machine learning.

PloS one Jan 1, 2025
Elevated consumption of sugar-sweetened beverages (SSBs) has been associated with an increase in obesity, type 2 diabetes, and other non-communicable diseases (NCDs), a significant health and economic burden on Mongolia. To address this, the governme...
Young Adult Adult Male Middle Aged Quality-Adjusted Life Years Humans Obesity Sugar-Sweetened Beverages Adolescent Machine Learning Cost-Benefit Analysis Female Taxes Markov Chains Disability-Adjusted Life Years Models, Economic Mongolia
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Software with artificial intelligence-derived algorithms for analysing CT brain scans in people with a suspected acute stroke: a systematic review and cost-effectiveness analysis.

Health technology assessment (Winchester, England) Mar 1, 2024
BACKGROUND: Artificial intelligence-derived software technologies have been developed that are intended to facilitate the review of computed tomography brain scans in patients with suspected stroke.
Algorithms Brain Tomography, X-Ray Computed Stroke Cost-Benefit Analysis Humans Artificial Intelligence Software Quality-Adjusted Life Years Technology Assessment, Biomedical Computed Tomography Angiography Cost-Effectiveness Analysis
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Robot-assisted training compared with an enhanced upper limb therapy programme and with usual care for upper limb functional limitation after stroke: the RATULS three-group RCT.

Health technology assessment (Winchester, England) Oct 1, 2020
BACKGROUND: Loss of arm function is common after stroke. Robot-assisted training may improve arm outcomes.
Stroke Rehabilitation Single-Blind Method Activities of Daily Living Cost-Benefit Analysis Models, Economic United Kingdom State Medicine Upper Extremity Quality-Adjusted Life Years Technology Assessment, Biomedical Quality of Life Severity of Illness Index Recovery of Function Robotics Aged Adult Male Middle Aged Humans Female
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[Retreatment strategies for the patients with HCV infection].

Przeglad epidemiologiczny Jan 1, 2005
Despite recent advances in the treatment of chronic hepatitis C, especially introduction of combined therapy with pegylated interferons with ribavirin, significant number of patients fails to achieve sustained virologic response. Such patients may be...
Ribavirin Recurrence Quality-Adjusted Life Years Humans Interferon-alpha Retreatment Treatment Outcome Antiviral Agents Drug Therapy, Combination Polyethylene Glycols Randomized Controlled Trials as Topic Recombinant Proteins Hepatitis C, Chronic Interferon alpha-2 Drug Administration Schedule
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