AIMC Topic: Quality-Adjusted Life Years

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Patient selection for proton therapy: a radiobiological fuzzy Markov model incorporating robust plan analysis.

Physical and engineering sciences in medicine
While proton therapy can offer increased sparing of healthy tissue compared with X-ray therapy, it can be difficult to predict whether a benefit can be expected for an individual patient. Predictive modelling may aid in this respect. However, the pre...

Cost-effectiveness of targeted screening for the identification of patients with atrial fibrillation: evaluation of a machine learning risk prediction algorithm.

Journal of medical economics
As many cases of atrial fibrillation (AF) are asymptomatic, patients often remain undiagnosed until complications (e.g. stroke) manifest. Risk-prediction algorithms may help to efficiently identify people with undiagnosed AF. However, the cost-effec...

Artificial neural network metamodel for sensitivity analysis in a total hip replacement health economic model.

Expert review of pharmacoeconomics & outcomes research
: Metamodels have been used to approximate complex simulations and have many applications with sensitivity analysis, optimization, etc. However, their use in health economics is very limited. Application of artificial neural network (ANN) with a heal...

Broadening the Perspective of Cost-Effectiveness Modeling in Chronic Obstructive Pulmonary Disease: A New Patient-Level Simulation Model Suitable to Evaluate Stratified Medicine.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
OBJECTIVES: To develop a health economic model that included a great diversity of patient characteristics and outcomes for chronic obstructive pulmonary disease (COPD), which can be used to inform decisions about stratified medicine in COPD.

Can Robot-Assisted Unicompartmental Knee Arthroplasty Be Cost-Effective? A Markov Decision Analysis.

The Journal of arthroplasty
BACKGROUND: Unicompartmental knee arthroplasty (UKA) is a treatment option for single-compartment knee osteoarthritis. Robotic assistance may improve survival rates of UKA, but the cost-effectiveness of robot-assisted UKA is unknown. The purpose of t...

Clinical and economic effectiveness of Schroth therapy in adolescent idiopathic scoliosis: insights from a machine learning- and active learning-based real-world study.

Journal of orthopaedic surgery and research
BACKGROUND: Adolescent idiopathic scoliosis (AIS) is a prevalent musculoskeletal condition affecting approximately 2-3% of the adolescent population. Although exercise-based therapeutic interventions are increasingly employed as non-surgical alternat...

Cost-effectiveness of opportunistic osteoporosis screening using chest radiographs with deep learning in Germany.

Aging clinical and experimental research
BACKGROUND: Osteoporosis is often underdiagnosed due to limitations in traditional screening methods, leading to missed early intervention opportunities. AI-driven screening using chest radiographs could improve early detection, reduce fracture risk,...

Protocol for evaluating the cost-effectiveness of Mongolia's sugar-sweetened beverages tax using double machine learning.

PloS one
Elevated consumption of sugar-sweetened beverages (SSBs) has been associated with an increase in obesity, type 2 diabetes, and other non-communicable diseases (NCDs), a significant health and economic burden on Mongolia. To address this, the governme...