BACKGROUND/AIMS: This work aims to observe the effects of mast cell (MC) chymase on activation, proliferation and transdifferentiation of hepatic stellate cells (HSCs) and to discuss the role of chymase in development of liver fibrosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience
May 6, 2015
Trunk motor control is crucial for postural stability and propulsion after low thoracic spinal cord injury (SCI) in animals and humans. Robotic rehabilitation aimed at trunk shows promise in SCI animal models and patients. However, little is known ab...
Use of laboratory animals for systemic toxicity testing is subject to strong ethical and regulatory constraints, but few alternatives are yet available. One possible approach to predict systemic toxicity of chemicals in the absence of experimental da...
International journal of medicinal mushrooms
Jan 1, 2015
We examined the hepatoprotective activity of Inonotus obliquus water extract (IO-W) against tert-butyl hydroperoxide (t-BHP)-induced oxidative liver injury in the primary cultured rat hepatocyte. The 50% radical scavenging concentrations (SC50s) of I...
International journal of medicinal mushrooms
Jan 1, 2015
Alcohol abuse and alcoholism remain one of the major health issues worldwide, especially in developing countries. The protective effect of Phellinus rimosus against acute alcohol-induced lipid peroxidation in the liver, kidney, and brain as well as i...
International journal of medicinal mushrooms
Jan 1, 2015
Neurodegenerative disease is defined as a deterioration of the nervous system in the intellectual and cognitive capabilities. Statistics show that more than 80-90 million individuals age 65 and above in 2050 may be affected by neurodegenerative condi...
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