AIMC Topic: Reproducibility of Results

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Machine learning combined with non-targeted LC-HRMS analysis for a risk warning system of chemical hazards in drinking water: A proof of concept.

Talanta
Guaranteeing clean drinking water to the global population is becoming more challenging, because of the cases of water scarcity across the globe, growing population, and increased chemical footprint of this population. Existing targeted strategies fo...

Machine learning of brain gray matter differentiates sex in a large forensic sample.

Human brain mapping
Differences between males and females have been extensively documented in biological, psychological, and behavioral domains. Among these, sex differences in the rate and typology of antisocial behavior remains one of the most conspicuous and enduring...

Learning protein binding affinity using privileged information.

BMC bioinformatics
BACKGROUND: Determining protein-protein interactions and their binding affinity are important in understanding cellular biological processes, discovery and design of novel therapeutics, protein engineering, and mutagenesis studies. Due to the time an...

Simultaneous NODDI and GFA parameter map generation from subsampled q-space imaging using deep learning.

Magnetic resonance in medicine
PURPOSE: To develop a robust multidimensional deep-learning based method to simultaneously generate accurate neurite orientation dispersion and density imaging (NODDI) and generalized fractional anisotropy (GFA) parameter maps from undersampled q-spa...

An unsupervised and customizable misspelling generator for mining noisy health-related text sources.

Journal of biomedical informatics
BACKGROUND: Data collection and extraction from noisy text sources such as social media typically rely on keyword-based searching/listening. However, health-related terms are often misspelled in such noisy text sources due to their complex morphology...

Segmentation of the Proximal Femur from MR Images using Deep Convolutional Neural Networks.

Scientific reports
Magnetic resonance imaging (MRI) has been proposed as a complimentary method to measure bone quality and assess fracture risk. However, manual segmentation of MR images of bone is time-consuming, limiting the use of MRI measurements in the clinical p...

Predictable and precise template-free CRISPR editing of pathogenic variants.

Nature
Following Cas9 cleavage, DNA repair without a donor template is generally considered stochastic, heterogeneous and impractical beyond gene disruption. Here, we show that template-free Cas9 editing is predictable and capable of precise repair to a pre...