AIMC Topic: Respiratory Tract Infections

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Application of MALDI-TOF MS and machine learning for the detection of SARS-CoV-2 and non-SARS-CoV-2 respiratory infections.

Microbiology spectrum
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) could aid the diagnosis of acute respiratory infections (ARIs) owing to its affordability and high-throughput capacity. MALDI-TOF MS has been proposed for use...

Early prediction of pediatric asthma in the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort using machine learning.

Pediatric research
BACKGROUND: Early identification of children at risk of asthma can have significant clinical implications for effective intervention and treatment. This study aims to disentangle the relative timing and importance of early markers of asthma.

Prediction of Lung Infection during Palliative Chemotherapy of Lung Cancer Based on Artificial Neural Network.

Computational and mathematical methods in medicine
Lung infection seriously affects the effect of chemotherapy in patients with lung cancer and increases pain. The study is aimed at establishing the prediction model of infection in patients with lung cancer during chemotherapy by an artificial neural...

A quite sensitive fluorescent loop-mediated isothermal amplification for rapid detection of respiratory syncytial virus.

Journal of infection in developing countries
INTRODUCTION: Human respiratory syncytial virus (hRSV) is a common respiratory virus closely related to respiratory tract infection (RTI). Rapid and accurate detection of hRSV is urgently needed to reduce the high morbidity and mortality due to hRSV ...

Comparison of the Abbott Architect BRAHMS and the Biomérieux Vidas BRAHMS Procalcitonin Assays.

The journal of applied laboratory medicine
BACKGROUND: Procalcitonin (PCT) is a well-established marker for bacterial infection. Recently the US Food and Drug Administration approved the expanded use of this biomarker to guide clinical decisions for antibiotic treatment in patients with lower...

Controlling testing volume for respiratory viruses using machine learning and text mining.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Viral testing for pediatric inpatients with respiratory symptoms is common, with considerable associated charges. In an attempt to reduce testing volumes, we studied whether data available at the time of admission could aid in identifying children wi...

Herpes simplex virus in bronchoalveolar lavage fluid of medical intensive care unit patients: Association with lung injury and outcome.

Journal of critical care
PURPOSE: In intensive care unit (ICU) patients in whom bronchoalveolar lavage fluid (BALF) was analyzed for suspected infectious pulmonary disease, we investigated the association of herpes simplex virus (HSV) in the BALF with lung injury and patient...

Diagnostic Machine Learning Models of Infectious Mononucleosis in Children Based on Clinical Data: A Retrospective Multicenter Study.

Journal of medical virology
The clinical manifestations of infectious mononucleosis (IM) and acute respiratory tract infections (ARTI) exhibit significant similarities. We aim to develop cost-efficient models for IM in children utilizing the Shapley Additive explanation (SHAP) ...

Machine Learning-Based Prediction to Support ICU Admission Decision Making among Very Old Patients with Respiratory Infections: A Proof of Concept on a Nationwide Population-Based Cohort Study.

Medical decision making : an international journal of the Society for Medical Decision Making
BackgroundIntensive care unit (ICU) hospitalizations of very old patients with acute respiratory infection have risen. The decision-making process for ICU admission is multifaceted, and the prediction of long-term survival outcome is an important com...

Identification of Elderly Patients with Lower Respiratory Tract Infection by Artificial Intelligence Analysis of Cough Pattern Sounds.

Discovery medicine
BACKGROUND: Automatic recognition of cough sounds shows promise in the diagnosis of respiratory conditions. This study investigated the diagnostic value of cough sounds in elderly patients with lower respiratory tract infection (LRTI).