The cortico-striatal-thalamo-cortical (CSTC) pathway is a brain circuit that controls movement execution, habit formation and reward. Hyperactivity in the CSTC pathway is involved in obsessive compulsive disorder (OCD), a neuropsychiatric disorder ch...
The mechanisms of decision-making and action selection are generally thought to be under the control of parallel cortico-subcortical loops connecting back to distinct areas of cortex through the basal ganglia and processing motor, cognitive and limbi...
Neural networks : the official journal of the International Neural Network Society
Aug 24, 2016
The goal of reinforcement learning is to learn an optimal policy which controls an agent to acquire the maximum cumulative reward. The model-based reinforcement learning approach learns a transition model of the environment from data, and then derive...
The brain enables animals to behaviorally adapt in order to survive in a complex and dynamic environment, but how reward-oriented behaviors are achieved and computed by its underlying neural circuitry is an open question. To address this concern, we ...
Cortex; a journal devoted to the study of the nervous system and behavior
Jul 15, 2016
Single neurons in the primate orbitofrontal cortex respond when an expected reward is not obtained, and behaviour must change. The human lateral orbitofrontal cortex is activated when non-reward, or loss occurs. The neuronal computation of this negat...
Neural networks : the official journal of the International Neural Network Society
May 24, 2016
Decision-making is a flexible process dependent on the accumulation of various kinds of information; however, the corresponding neural mechanisms are far from clear. We extended a layered model of the frontal eye field to a learning-based model, usin...
International journal of neural systems
Apr 28, 2016
Classification and sequence learning are relevant capabilities used by living beings to extract complex information from the environment for behavioral control. The insect world is full of examples where the presentation time of specific stimuli shap...
Neurons in higher cortical areas, such as the prefrontal cortex, are often tuned to a variety of sensory and motor variables, and are therefore said to display mixed selectivity. This complexity of single neuron responses can obscure what information...
At around 7 months of age, human infants begin to reliably produce well-formed syllables containing both consonants and vowels, a behavior called canonical babbling. Over subsequent months, the frequency of canonical babbling continues to increase. H...
Transitive inference (the ability to infer that B > D given that B > C and C > D) is a widespread characteristic of serial learning, observed in dozens of species. Despite these robust behavioral effects, reinforcement learning models reliant on rewa...