AIMC Topic: Risk Assessment

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Association of time to colonoscopy after a positive fecal test result and fecal hemoglobin concentration with risk of advanced colorectal neoplasia.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
BACKGROUND: We evaluated the risk of advanced colorectal neoplasia (ACRN) and colorectal cancer (CRC) according to time to colonoscopy after positive fecal immunochemical test (FIT), fecal hemoglobin concentration, and combination of both.

Constipation and risk of death and cardiovascular events.

Atherosclerosis
BACKGROUND AND AIMS: Constipation is one of the most frequent symptoms encountered in daily clinical practice and is implicated in the development of atherosclerosis, potentially through altered gut microbiota. However, little is known about its asso...

Review of water quality criteria for water reuse and risk-based implications for irrigated produce under the FDA Food Safety Modernization Act, produce safety rule.

Environmental research
Questions related to the safety of alternative water sources, such as recycled water or reclaimed water (including grey water, produced water, return flows, and recycled wastewater), for produce production have been largely un-explored at the detail ...

Survival outcome prediction in cervical cancer: Cox models vs deep-learning model.

American journal of obstetrics and gynecology
BACKGROUND: Historically, the Cox proportional hazard regression model has been the mainstay for survival analyses in oncologic research. The Cox proportional hazard regression model generally is used based on an assumption of linear association. How...

Diagnosis of thyroid cancer using deep convolutional neural network models applied to sonographic images: a retrospective, multicohort, diagnostic study.

The Lancet. Oncology
BACKGROUND: The incidence of thyroid cancer is rising steadily because of overdiagnosis and overtreatment conferred by widespread use of sensitive imaging techniques for screening. This overall incidence growth is especially driven by increased diagn...

Machine Learning Models for Genetic Risk Assessment of Infants with Non-syndromic Orofacial Cleft.

Genomics, proteomics & bioinformatics
The isolated type of orofacial cleft, termed non-syndromic cleft lip with or without cleft palate (NSCL/P), is the second most common birth defect in China, with Asians having the highest incidence in the world. NSCL/P involves multiple genes and com...

Spatiotemporal continuous estimates of PM concentrations in China, 2000-2016: A machine learning method with inputs from satellites, chemical transport model, and ground observations.

Environment international
Ambient exposure to fine particulate matter (PM) is known to harm public health in China. Satellite remote sensing measurements of aerosol optical depth (AOD) were statistically associated with in-situ observations after 2013 to predict PM concentrat...

Leveraging auxiliary measures: a deep multi-task neural network for predictive modeling in clinical research.

BMC medical informatics and decision making
BACKGROUND: Accurate predictive modeling in clinical research enables effective early intervention that patients are most likely to benefit from. However, due to the complex biological nature of disease progression, capturing the highly non-linear in...

Application of data mining methods to improve screening for the risk of early gastric cancer.

BMC medical informatics and decision making
BACKGROUND: Although gastric cancer is a malignancy with high morbidity and mortality in China, the survival rate of patients with early gastric cancer (EGC) is high after surgical resection. To strengthen diagnosing and screening is the key to impro...

Distillation of the clinical algorithm improves prognosis by multi-task deep learning in high-risk Neuroblastoma.

PloS one
We introduce the CDRP (Concatenated Diagnostic-Relapse Prognostic) architecture for multi-task deep learning that incorporates a clinical algorithm, e.g., a risk stratification schema to improve prognostic profiling. We present the first application ...