AIMC Topic: Risk Factors

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Genetic Risk Scores in Stroke Research and Care.

Stroke
Stroke remains a leading cause of death and disability worldwide. While well-established risk factors play a major role, genetic predisposition is a crucial determinant of stroke susceptibility, with heritability estimates up to 39% for ischemic stro...

Development and Validation of Ultrasound Hemodynamic-based Prediction Models for Acute Kidney Injury After Renal Transplantation.

Academic radiology
RATIONALE AND OBJECTIVES: Acute kidney injury (AKI) post-renal transplantation often has a poor prognosis. This study aimed to identify patients with elevated risks of AKI after kidney transplantation.

Predicting rheumatoid arthritis in the middle-aged and older population using patient-reported outcomes: insights from the SHARE cohort.

International journal of medical informatics
BACKGROUND: In light of global population aging and the increasing prevalence of Rheumatoid Arthritis (RA) with age, strategies are needed to address this public health challenge. Machine learning (ML) may play a vital role in early identification of...

Prediction of first attempt of suicide in early adolescence using machine learning.

Journal of affective disorders
BACKGROUND: Suicide is the second leading cause of death among early adolescents, yet the first onset of suicide attempts during this critical developmental period remains poorly understood. This study aimed to identify key characteristics associated...

Interpretable lung cancer risk prediction using ensemble learning and XAI based on lifestyle and demographic data.

Computational biology and chemistry
Lung cancer is a leading cause of cancer-related death worldwide. The early and accurate detection of lung cancer is crucial for improving patient outcomes. Traditional predictive models often lack the accuracy and interpretability required in clinic...

Role of Brain Age Gap as a Mediator in the Relationship Between Cognitive Impairment Risk Factors and Cognition.

Neurology
BACKGROUND AND OBJECTIVES: Cerebrovascular disease (CeVD) and cognitive impairment risk factors contribute to cognitive decline, but the role of brain age gap (BAG) in mediating this relationship remains unclear, especially in Southeast Asian populat...

Surveillance and Surgical Salvage Treatment for Endoscopically Removed T1 Colorectal Cancers.

Gut and liver
Endoscopic submucosal dissection (ESD) enables en-bloc resection of large lesions more than 20 mm in size. Therefore, the use of ESD has gained broader acceptance for clinical applications globally. Previous reports on long-term outcomes after ESD, w...

A Transformer-Based Framework for Counterfactual Estimation of Antihypertensive Treatment Effect on COVID-19 Infection Risk - A Proof-of-Concept Study.

American journal of hypertension
BACKGROUND: Transformer-based neural networks excel in modelling high-dimensional, time-series data with complex dependencies. This proof-of-concept study applies a transformer-X-learner framework to estimate treatment effects using real-world data, ...

Machine learning-driven risk prediction and feature identification for major depressive disorder and its progression: an exploratory study based on five years of longitudinal data from the US national health survey.

Journal of affective disorders
BACKGROUND: Major depressive disorder (MDD) presents significant public health challenges due to its increasing prevalence and complex risk factors. This study systematically analyzed data from 2019 to 2023 to explore trends in MDD incidence, symptom...

Artificial Intelligence to Improve Blood Pressure Control: A State-of-the-Art Review.

American journal of hypertension
Hypertension remains a major global health challenge, contributing to significant morbidity and mortality. Advances in artificial intelligence (AI) and machine learning (ML) are transforming hypertension care by enhancing blood pressure (BP) measurem...