AIMC Topic: ROC Curve
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Screening biomarkers related to cholesterol metabolism in osteoarthritis based on transcriptomics.
Scientific reports
Jul 1, 2025
Cholesterol metabolism-related genes (CMRGs) have been associated with osteoarthritis (OA), but their specific regulatory mechanisms remain unclear. This study aimed to investigate the role of CMRGs in OA and provide new insights into its treatment. ...
Ultrasound-based classification of follicular thyroid Cancer using deep convolutional neural networks with transfer learning.
Scientific reports
Jul 1, 2025
This study aimed to develop and validate convolutional neural network (CNN) models for distinguishing follicular thyroid carcinoma (FTC) from follicular thyroid adenoma (FTA). Additionally, this current study compared the performance of CNN models wi...
Interpretable machine learning for predicting isolated basal septal hypertrophy.
PloS one
Jun 30, 2025
BACKGROUND: The basal septal hypertrophy(BSH) is an often under-recognized morphological change in the left ventricle. This is a common echocardiographic finding with a prevalence of approximately 7-20%, which may indicate early structural and functi...
Improving a data mining based diagnostic support tool for rare diseases on the example of M. Fabry: Gender differences need to be taken into account.
PloS one
Jun 30, 2025
BACKGROUND: Rare diseases often present with a variety of clinical symptoms and therefore are challenging to diagnose. Fabry disease is an x-linked rare metabolic disorder. The severity of symptoms is usually different in men and women. Since therape...
Radiomic 'Stress Test': exploration of a deep learning radiomic model in a high-risk prospective lung nodule cohort.
BMJ open respiratory research
Jun 27, 2025
BACKGROUND: Indeterminate pulmonary nodules (IPNs) are commonly biopsied to ascertain a diagnosis of lung cancer, but many are ultimately benign. The Lung Cancer Prediction (LCP) score is a commercially available deep learning radiomic model with str...
Machine learning for the prediction of spontaneous preterm birth using early second and third trimester maternal blood gene expression: A cautionary tale.
PloS one
Jun 27, 2025
Spontaneous preterm birth (sPTB) remains a significant global health challenge and a leading cause of neonatal mortality and morbidity. Despite advancements in neonatal care, the prediction of sPTB remains elusive, in part due to complex etiologies a...
Comprehensive analysis and experimental validation of BST1 as a novel diagnostic biomarker for pediatric sepsis using multiple machine learning algorithms.
European journal of pediatrics
Jun 25, 2025
Bone marrow stromal cell antigen-1 (BST1) expression is elevated in a variety of human diseases, but its relationship with pediatric sepsis is unclear. This study aimed to investigate the expression of BST1 in pediatric sepsis patients and its value ...
The early prediction of neonatal necrotizing enterocolitis in high-risk newborns based on two medical center clinical databases.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Jun 23, 2025
: Early identification and timely preventive interventions play an essential role for improving the prognosis of newborns with necrotizing enterocolitis (NEC). Thus, establishing a novel and simple prediction model is of great clinical significance. ...
Realistic fundus photograph generation for improving automated disease classification.
The British journal of ophthalmology
Jun 23, 2025
AIMS: This study aims to investigate whether denoising diffusion probabilistic models (DDPMs) could generate realistic retinal images, and if they could be used to improve the performance of a deep convolutional neural network (CNN) ensemble for mult...
Development of a Machine Learning-Based Predictive Model for Postoperative Delirium in Older Adult Intensive Care Unit Patients: Retrospective Study.
Journal of medical Internet research
Jun 19, 2025
BACKGROUND: Delirium is a prevalent phenomenon among patients admitted to the geriatric intensive care unit (ICU) and can adversely impact prognosis and augment the risk of complications.
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