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Squamous Cell Carcinoma of Head and Neck

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Predicting TNFRSF4 expression and prognosis in head and neck squamous cell carcinoma tissue: a pathological image analysis approach.

Polish journal of pathology : official journal of the Polish Society of Pathologists
Head and neck squamous cell carcinoma (HNSCC) exhibits a poor 5-year survival rate. TNFRSF4 is gaining attention in tumor therapy. The objective of this study was to forecast the expression of TNFRSF4 in HNSCC tissue using analysis of pathological im...

Machine-learning derived identification of prognostic signature to forecast head and neck squamous cell carcinoma prognosis and drug response.

Frontiers in immunology
INTRODUCTION: Head and neck squamous cell carcinoma (HNSCC), a highly heterogeneous malignancy is often associated with unfavorable prognosis. Due to its unique anatomical position and the absence of effective early inspection methods, surgical inter...

Enhancing surgical precision in squamous cell carcinoma of the head and neck: Hyperspectral imaging and artificial intelligence for improved margin assessment in an ex vivo setting.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
BACKGROUND: Head and neck cancers, constituting 3-5% of all cancer cases, often require surgical resection for optimal outcomes. Achieving complete resection (R0) is crucial, but current methods, relying on white light endoscopy and microscopy, have ...

Applicability of Artificial Intelligence Analysis in Oral Cytopathology: A Pilot Study.

Acta cytologica
INTRODUCTION: Oral cancer, especially oral squamous cell carcinoma (OSCC), is a global health challenge due to factors such as late detection and high mortality rates. Early detection is essential through monitoring by healthcare professionals. Cytop...

Artificial intelligence for image recognition in diagnosing oral and oropharyngeal cancer and leukoplakia.

Scientific reports
Visual diagnosis is one of the key features of squamous cell carcinoma of the oral cavity (OSCC) and oropharynx (OPSCC), both subsets of head and neck squamous cell carcinoma (HNSCC) with a heterogeneous clinical appearance. Advancements in artificia...

Classifying tumour infiltrating lymphocytes in oral squamous cell carcinoma histopathology using joint learning framework.

Scientific reports
Oral squamous cell carcinoma (OSCC) is the most common form of oral cancer, with increasing global incidence and have poor prognosis. Tumour-infiltrating lymphocytes (TILs) are recognized as a key prognostic indicator and play a vital role in OSCC gr...

Leveraging Deep Learning for Immune Cell Quantification and Prognostic Evaluation in Radiotherapy-Treated Oropharyngeal Squamous Cell Carcinomas.

Laboratory investigation; a journal of technical methods and pathology
The tumor microenvironment plays a critical role in cancer progression and therapeutic responsiveness, with the tumor immune microenvironment (TIME) being a key modulator. In head and neck squamous cell carcinomas (HNSCCs), immune cell infiltration s...

Machine learning prediction model for oral mucositis risk in head and neck radiotherapy: a preliminary study.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
PURPOSE: Oral mucositis (OM) reflects a complex interplay of several risk factors. Machine learning (ML) is a promising frontier in science, capable of processing dense information. This study aims to assess the performance of ML in predicting OM ris...

Development and validation of MRI-derived deep learning score for non-invasive prediction of PD-L1 expression and prognostic stratification in head and neck squamous cell carcinoma.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Immunotherapy has revolutionized the treatment landscape for head and neck squamous cell carcinoma (HNSCC) and PD-L1 combined positivity score (CPS) scoring is recommended as a biomarker for immunotherapy. Therefore, this study aimed to d...

Multiple machine learning-based integrations of multi-omics data to identify molecular subtypes and construct a prognostic model for HNSCC.

Hereditas
BACKGROUND: Immunotherapy has introduced new breakthroughs in improving the survival of head and neck squamous cell carcinoma (HNSCC) patients, yet drug resistance remains a critical challenge. Developing personalized treatment strategies based on th...