International journal of pharmaceutics
Nov 9, 2025
PURPOSE: Gastric adenocarcinoma is a highly aggressive malignancy characterized by a complex tumor microenvironment. Nano-curcumin liposomes hold great potential in inhibiting tumor growth and survival, as well as inducing cuproptosis and oxidative s...
Gastric cancer (GC) continues to pose a significant global health burden with persistent diagnostic challenges, especially in the detection of early-stage GC. Herein, a strand displacement reaction-mediated nucleic acid amplifier based on the spatial...
OBJECTIVE: Distant metastasis (DM) of gastric cancer (GC) represents a significant health challenge due to its high mortality rates, necessitating advancements in early detection and management strategies. The objective of this study was to create a ...
Gastric cancer is a leading cause of cancer-related mortality and highlights the need for early detection of gastric cancer and Helicobacter pylori (HP) infection, which is a major risk factor. Early non-invasive and convenient diagnostic tools capab...
BACKGROUND: Current cancer staging methods cannot accurately predict survival outcomes and therapeutic benefits in cancer patients. Digital pathomics, a rapidly evolving field, holds significant potential to revolutionize disease evaluation.
Gastric cancer (GC) is a highly heterogeneous disease that requires highly accurate prognostic models. Machine learning is a powerful tool for identifying predictive biomarkers and developing prognostic models. Here, we aim to integrate bioinformatic...
Epstein-Barr virus (EBV) associated gastric cancer, accounting for ~ 9% of all gastric cancers, has unique pathologic, genomic, and clinical features and is linked to a better prognosis. Therefore, we aim to develop and validate a robust deep learnin...
Stomach adenocarcinoma (STAD), the most prevalent histological subtype of gastric cancer, exhibits high heterogeneity and poor prognosis, posing significant therapeutic challenges. Parthanatos, a distinct form of regulated cell death mediated by poly...
Lymph node metastasis (LNM) is an independent prognostic factor for patients with gastric cancer (GC), and an accurate lymph node (LN) staging system is crucial for guiding adjuvant therapy and assessing patient prognosis. The most commonly used stag...
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