OBJECTIVES: In this paper, an alignment-free method for DNA barcode classification that is based on both a spectral representation and a neural gas network for unsupervised clustering is proposed.
Alternative splicing acts on transcripts from almost all human multi-exon genes. Notwithstanding its ubiquity, fundamental ramifications of splicing on protein expression remain unresolved. The number and identity of spliced transcripts that form sta...
This paper describes a supervised machine learning approach for identifying heart disease risk factors in clinical text, and assessing the impact of annotation granularity and quality on the system's ability to recognize these risk factors. We utiliz...
Neural networks : the official journal of the International Neural Network Society
Jun 19, 2015
Discriminative clustering is an unsupervised learning framework which introduces the discriminative learning rule of supervised classification into clustering. The underlying assumption is that a good partition (clustering) of the data should yield h...
The development of realistic neuroanatomical models of peripheral nerves for simulation purposes requires the reconstruction of the morphology of the myelinated fibres in the nerve, including their nodes of Ranvier. Currently, this information has to...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Jun 8, 2015
This paper presents a novel method for feature extraction from electroencephalogram (EEG) signals using empirical mode decomposition (EMD). Its use is motivated by the fact that the EMD gives an effective time-frequency analysis of nonstationary sign...
BACKGROUND: Activities of daily living (ADL) are important for quality of life. They are indicators of cognitive health status and their assessment is a measure of independence in everyday living. ADL are difficult to reliably assess using questionna...
Computational intelligence and neuroscience
May 27, 2015
A novel semisupervised extreme learning machine (ELM) with clustering discrimination manifold regularization (CDMR) framework named CDMR-ELM is proposed for semisupervised classification. By using unsupervised fuzzy clustering method, CDMR framework ...
This paper presents data-driven methods for echocardiogram enhancement. Existing denoising algorithms typically rely on a single noise model, and do not generalize to the composite noise sources typically found in real-world echocardiograms. Our meth...
Neural networks : the official journal of the International Neural Network Society
May 9, 2015
Hierarchical probabilistic models, such as Gaussian mixture models, are widely used for unsupervised learning tasks. These models consist of observable and latent variables, which represent the observable data and the underlying data-generation proce...
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