Biochemical and biophysical research communications
40239539
Molecular surface analysis can provide a high-dimensional, rich representation of molecular properties and interactions, which is crucial for enabling powerful predictive modeling and rational molecular design across diverse scientific and technologi...
The development of lightweight, corrosion-resistant metallic lattice structures has gained significant attention in aerospace, defense, and structural applications, where material durability and weight optimization are critical. This study investigat...
Coagulation within blood vessels is a major cause of cardiovascular disease and global mortality, highlighting the urgent need for effective anticoagulant strategies. In this study, we introduce a dynamic and highly efficient anticoagulant platform, ...
Native ion mobility-mass spectrometry combined with collision-induced unfolding (CIU) is a powerful analytical method for protein characterization, offering insights into structural stability and enabling the differentiation of analytes with similar ...
Previous research showed that a peptide composed of three tyrosines (YYY) can turn into organic glass and cause strong adhesion between substrates via evaporation. However, the mechanisms of these processes remain unclear, and the exploration of appl...
PURPOSE: Predicting powder blend flowability is necessary for pharmaceutical manufacturing but challenging and resource-intensive. The purpose was to develop machine learning (ML) models to help predict flowability across multiple flow categories, id...
The relationship between Superparamagnetic Iron Oxide Nanoparticles (SPIONs) surface chemistry and their toxicological outcomes is crucial for biomedical applications, including drug delivery and imaging diagnostics. SPIONs' surface properties-such a...
Research on nanoplastic (NP) toxicity and their "carrier effects" on human health remains nascent, especially for real-time, in situ monitoring of metabolic reactions in live cells. Herein, we developed smart surface-enhanced Raman spectroscopy (SERS...
The adsorption of biomolecules on the surface of nanomaterials (NMs) is a critical determinant of their behavior, toxicity, and efficacy in biological systems. Experimental testing of these phenomena is often costly or complicated. Computational appr...
Lipid nanoparticles (LNPs) are highly effective carriers for gene therapies, including mRNA and siRNA delivery, due to their ability to transport nucleic acids across biological membranes, low cytotoxicity, improved pharmacokinetics, and scalability....