AIMC Topic: Survival Analysis

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Alternative splicing associated with cancer stemness in kidney renal clear cell carcinoma.

BMC cancer
BACKGROUD: Cancer stemness is associated with metastases in kidney renal clear cell carcinoma (KIRC) and negatively correlates with immune infiltrates. Recent stemness evaluation methods based on the absolute expression have been proposed to reveal t...

A different overview of staging PET/CT images in patients with esophageal cancer: the role of textural analysis with machine learning methods.

Annals of nuclear medicine
OBJECTIVE: This study evaluates the ability of several machine learning (ML) algorithms, developed using volumetric and texture data extracted from baseline F-FDG PET/CT studies performed initial staging of patient with esophageal cancer (EC), to pre...

Integration of machine learning and genome-scale metabolic modeling identifies multi-omics biomarkers for radiation resistance.

Nature communications
Resistance to ionizing radiation, a first-line therapy for many cancers, is a major clinical challenge. Personalized prediction of tumor radiosensitivity is not currently implemented clinically due to insufficient accuracy of existing machine learnin...

Glycemic and lipid variability for predicting complications and mortality in diabetes mellitus using machine learning.

BMC endocrine disorders
INTRODUCTION: Recent studies have reported that HbA1c and lipid variability is useful for risk stratification in diabetes mellitus. The present study evaluated the predictive value of the baseline, subsequent mean of at least three measurements and v...

Accurate cancer phenotype prediction with AKLIMATE, a stacked kernel learner integrating multimodal genomic data and pathway knowledge.

PLoS computational biology
Advancements in sequencing have led to the proliferation of multi-omic profiles of human cells under different conditions and perturbations. In addition, many databases have amassed information about pathways and gene "signatures"-patterns of gene ex...

An Improved Muti-Task Learning Algorithm for Analyzing Cancer Survival Data.

IEEE/ACM transactions on computational biology and bioinformatics
Survival analysis is a popular branch of statistics. At present, many algorithms (like traditional multi-tasking learning model) cannot be applied well in practice because of censored data. Although using some model (like parametric regression model)...

Artificial neural networks versus LASSO regression for the prediction of long-term survival after surgery for invasive IPMN of the pancreas.

PloS one
Prediction of long-term survival in patients with invasive intraductal papillary mucinous neoplasm (IPMN) of the pancreas may aid in patient assessment, risk stratification and personalization of treatment. This study aimed to investigate the predict...

Predicting gastric cancer outcome from resected lymph node histopathology images using deep learning.

Nature communications
N-staging is a determining factor for prognostic assessment and decision-making for stage-based cancer therapeutic strategies. Visual inspection of whole-slides of intact lymph nodes is currently the main method used by pathologists to calculate the ...