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Tissue Engineering

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Soft robotic constrictor for in vitro modeling of dynamic tissue compression.

Scientific reports
Here we present a microengineered soft-robotic in vitro platform developed by integrating a pneumatically regulated novel elastomeric actuator with primary culture of human cells. This system is capable of generating dynamic bending motion akin to th...

Stereotactic technology for 3D bioprinting: from the perspective of robot mechanism.

Biofabrication
Three-dimensional (3D) bioprinting has been widely applied in the field of biomedical engineering because of its rapidly individualized fabrication and precisely geometric designability. The emerging demand for bioprinted tissues/organs with bio-insp...

Metamorphosis in Insect Muscle: Insights for Engineering Muscle-Based Actuators.

Tissue engineering. Part B, Reviews
One of the major limitations to advancing the development of soft robots is the absence of lightweight, effective soft actuators. While synthetic systems, such as pneumatics and shape memory alloys, have created important breakthroughs in soft actuat...

The future of bone regeneration: integrating AI into tissue engineering.

Biomedical physics & engineering express
Tissue engineering is a branch of regenerative medicine that harnesses biomaterial and stem cell research to utilise the body's natural healing responses to regenerate tissue and organs. There remain many unanswered questions in tissue engineering, w...

Recent progress in engineering functional biohybrid robots actuated by living cells.

Acta biomaterialia
Living cells are highly scalable biological actuators found in nature, and they are efficient technological solutions to actuate robotic systems. Recent advancements in biofabrication and tissue engineering have bridged the gap to interface muscle ce...

Machine Learning-Guided Three-Dimensional Printing of Tissue Engineering Scaffolds.

Tissue engineering. Part A
Various material compositions have been successfully used in 3D printing with promising applications as scaffolds in tissue engineering. However, identifying suitable printing conditions for new materials requires extensive experimentation in a time ...

Photonic artificial muscles: from micro robots to tissue engineering.

Faraday discussions
Light responsive shape-changing polymers are able to mimic the function of biological muscles accomplishing mechanical work in response to selected stimuli. A variety of manufacturing techniques and chemical processes can be employed to shape these m...

Machine learning to predict mesenchymal stem cell efficacy for cartilage repair.

PLoS computational biology
Inconsistent therapeutic efficacy of mesenchymal stem cells (MSCs) in regenerative medicine has been documented in many clinical trials. Precise prediction on the therapeutic outcome of a MSC therapy based on the patient's conditions would provide va...

A Coupled FEM-SPH Modeling Technique to Investigate the Contractility of Biohybrid Thin Films.

Advanced biosystems
Biohybrid actuators have the potential to overcome the limitations of traditional actuators employed in robotics, thanks to the unique features of living contractile muscle cells, which can be used to power artificial elements. This paper describes a...