AI Medical Compendium Topic

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GP or ChatGPT? Ability of large language models (LLMs) to support general practitioners when prescribing antibiotics.

The Journal of antimicrobial chemotherapy
INTRODUCTION: Large language models (LLMs) are becoming ubiquitous and widely implemented. LLMs could also be used for diagnosis and treatment. National antibiotic prescribing guidelines are customized and informed by local laboratory data on antimic...

Histological proven AI performance in the UKLS CT lung cancer screening study: Potential for workload reduction.

European journal of cancer (Oxford, England : 1990)
PURPOSE: Artificial intelligence (AI) could reduce lung cancer screening computer tomography (CT)-reading workload if used as a first-reader, ruling-out negative CT-scans at baseline. Evidence is lacking to support AI performance when compared to gol...

Development and validation of a convenient dementia risk prediction tool for diabetic population: A large and longitudinal machine learning cohort study.

Journal of affective disorders
BACKGROUND: Diabetes mellitus has been shown to increase the risk of dementia, with diabetic patients demonstrating twice the dementia incidence rate of non-diabetic populations. We aimed to develop and validate a novel machine learning-based dementi...

Identification of heart failure subtypes using transformer-based deep learning modelling: a population-based study of 379,108 individuals.

EBioMedicine
BACKGROUND: Heart failure (HF) is a complex syndrome with varied presentations and progression patterns. Traditional classification systems based on left ventricular ejection fraction (LVEF) have limitations in capturing the heterogeneity of HF. We a...

Identifying novel risk factors for aneurysmal subarachnoid haemorrhage using machine learning.

Scientific reports
Aneurysmal subarachnoid haemorrhage (aSAH) is a type of stroke with high mortality and morbidity. This study aimed to identify novel aSAH risk factors by combining machine learning (ML) and traditional statistical methods. Using the UK Biobank, we id...

Modifiable risk factors of vaccine hesitancy: insights from a mixed methods multiple population study combining machine learning and thematic analysis during the COVID-19 pandemic.

BMC medicine
BACKGROUND: Vaccine hesitancy, the delay in acceptance or reluctance to vaccinate, ranks among the top threats to global health. Identifying modifiable factors contributing to vaccine hesitancy is crucial for developing targeted interventions to incr...

Addressing underestimation and explanation of retinal fundus photo-based cardiovascular disease risk score: Algorithm development and validation.

Computers in biology and medicine
OBJECTIVE: To resolve the underestimation problem and investigate the mechanism of the AI model which employed to predict cardiovascular disease (CVD) risk scores from retinal fundus photos.

Generative AI-Enabled Therapy Support Tool for Improved Clinical Outcomes and Patient Engagement in Group Therapy: Real-World Observational Study.

Journal of medical Internet research
BACKGROUND: Cognitive behavioral therapy (CBT) is a highly effective treatment for depression and anxiety disorders. Nonetheless, a substantial proportion of patients do not respond to treatment. The lack of engagement with therapeutic materials and ...

An interpretable machine learning approach for detecting psoriatic arthritis in a UK primary care psoriasis cohort using electronic health records from the Clinical Practice Research Datalink.

Annals of the rheumatic diseases
OBJECTIVES: Develop an interpretable machine learning model to detect patients with newly diagnosed psoriatic arthritis (PsA) in a cohort of psoriasis patients and identify important clinical indicators of PsA in primary care.

Exploring the application of deep learning methods for polygenic risk score estimation.

Biomedical physics & engineering express
. Polygenic risk scores (PRS) summarise genetic information into a single number with clinical and research uses. Deep learning (DL) has revolutionised multiple fields, however, the impact of DL on PRSs has been less significant. We explore how DL ca...