AIMC Topic: Adenocarcinoma of Lung

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CellOMaps: A compact representation for robust classification of lung adenocarcinoma growth patterns.

Computers in biology and medicine
Lung adenocarcinoma (LUAD) is a morphologically heterogeneous disease, characterized by five primary histological growth patterns. The classification of such patterns is crucial due to their direct relation to prognosis but the high subjectivity and ...

Deep learning radiomics fusion model to predict visceral pleural invasion of clinical stage IA lung adenocarcinoma: a multicenter study.

Journal of cardiothoracic surgery
AIM: To assess the predictive performance, risk stratification capabilities, and auxiliary diagnostic utility of radiomics, deep learning, and fusion models in identifying visceral pleural invasion (VPI) in lung adenocarcinoma.

Combining graph neural network and Mamba to capture local and global tissue spatial relationships in whole slide images.

Scientific reports
In computational pathology, extracting and representing spatial features from gigapixel whole slide images (WSIs) are fundamental tasks, but due to their large size, WSIs are typically segmented into smaller tiles. A critical aspect of analyzing WSIs...

Artificial Intelligence-Guided Cancer Engineering for Tumor Normalization Executed by Tumor Lysosomal-Triggered Supramolecular Chiral Peptide.

ACS nano
Cancer engineering for tumor normalization offers a promising therapeutic strategy to reverse malignant cells and their supportive tumor microenvironment into a more benign state. Herein, an artificial intelligence (AI) approach was developed using m...

Successful Application of Artificial Intelligence-Assisted Analysis of Invasive Pulmonary Adenocarcinoma Less Than 6 mm in Size: A Case Report and Literature Review.

The clinical respiratory journal
INTRODUCTION: Screening of lung nodules helps on early diagnosis of lung cancer, especially invasive pulmonary adenocarcinoma. Artificial intelligence (AI) has been applied in diagnosis of cancers. We used the AI-assisted lung nodule diagnostic syste...

Image-Based Deep Learning Model for Predicting Lymph Node Metastasis in Lung Adenocarcinoma With CT ≤ 2 cm.

Thoracic cancer
BACKGROUND: Lymph node metastasis (LNM) poses a considerable threat to survival in lung adenocarcinoma. Currently, minor resection is the recommended surgical approach for small-diameter lung cancer. The accurate preoperative identification of LNM in...

Identifying Lipid Metabolism-Related Therapeutic Targets and Diagnostic Markers for Lung Adenocarcinoma by Mendelian Randomization and Machine Learning Analysis.

Thoracic cancer
BACKGROUND: Lipid metabolic disorders are emerging as a recognized influencing factors of lung adenocarcinoma (LUAD). This study aims to investigate the influence of lipid metabolism-related genes (LMRGs) on the diagnosis and treatment of LUAD and to...

Development of an immune-related gene signature applying Ridge method for improving immunotherapy responses and clinical outcomes in lung adenocarcinoma.

PeerJ
BACKGROUND: Lung adenocarcinoma (LUAD) is a major cause of cancer mortality. Considering the critical role of tumor infiltrating lymphocytes in effective immunotherapy, this study was designed to screen molecular markers related to tumor infiltrating...