AIMC Topic: Aged

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Detection of brain network abnormalities by graph invariants in Alzheimer's disease using MRI images.

Scientific reports
Alzheimer's disease is a major cause of dementia in older adults. It involves gradual changes in brain function that result in cognitive decline, affecting memory, reasoning, and executive skills. The accurate detection of structural abnormalities in...

LightMG-Net: an efficient lightweight deep neural network for multiclass grading of retinal detachment using handcrafted statistical mechanisms.

Scientific reports
Retinal detachment is a severely curable eye condition that becomes a genuine factor for the increased visual acuity worldwide. If neglected, it may result significant visual impairment in individuals aged 60 to 69 years. The successful cure percenta...

The global epidemiology, risk factors, and mortality prediction of nocardiosis: an easily missed opportunistic infection.

Scientific reports
This study was to comprehensively investigate the epidemiology of nocardiosis worldwide and develop an interpretable machine learning (ML) model to predict mortality in patients with nocardiosis. The PubMed and Web of Science databases were searched ...

Comparison of Machine Learning Models for Colon Cancer Survival: Predictive Modeling Approach.

JMIR cancer
BACKGROUND: Colon cancer is a leading cause of cancer-related deaths worldwide, with survival influenced by risk factors, treatment type, and patient characteristics. Traditional statistical models, such as Kaplan-Meier curves, have been widely used ...

Predicting arthritis risk with machine learning: Insights from the 2023 National Health Interview Survey data.

PloS one
Arthritis, a common chronic disease encompassing multiple subtypes of osteoarthritis and rheumatoid arthritis, was explored in this study as a risk-related factor based on data from the 2023 U.S. National Health Interview Survey (NHIS). The study inc...

Association of blood-based DNA methylation of lncRNAs with Alzheimer's disease diagnosis.

Clinical epigenetics
BACKGROUND: DNA methylation has shown great potential in Alzheimer's disease (AD) blood diagnosis. However, the ability of long non-coding RNAs (lncRNAs), which can be modified by DNA methylation, to serve as noninvasive biomarkers for AD diagnosis r...

Joint impact of stress hyperglycaemic ratio and glycaemic variability in patients with ischaemic stroke and machine learning for mortality prediction.

BMC neurology
BACKGROUND: The global burden of ischaemic stroke (IS) is high, which is potentially relevant to stress hyperglycemia ratio (SHR) and glycaemic variability (GV). This study aims to evaluate the combined effect of the SHR and GV with predict short-ter...

Cell-free DNA methylation and fragmentomics-based liquid biopsy for accurate esophageal cancer detection.

BMC cancer
BACKGROUND: Cell-free DNA is a promising source of biomarkers for early cancer detection and carries tumor-driven methylation and fragmentation features that have achieved good diagnostic efficacy across various cancers. However, there were no studie...

Machine learning-based clinical-radiomics model for predicting recurrence risk after radical surgery in sinonasal squamous cell carcinoma: a preliminary 2-year follow-up study.

BMC medical imaging
BACKGROUND: To construct and validate an optimal machine learning (ML)-based clinical-radiomics model integrating clinical and radiomics features for predicting recurrence risk within 2 years after radical surgery in patients with sinonasal squamous ...

Pre-operatively predicting kidney stone recurrence: integrating radiomic features and clinical variables using machine learning.

BMC medical imaging
BACKGROUND: Radiomics and artificial intelligence have shown strong predictive capabilities in urinary stone research, particularly concerning stone composition, characteristics, and treatment outcomes. However, the association of stone radiomics and...