AIMC Topic: Aged

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Improving care for amyotrophic lateral sclerosis with artificial intelligence and affective computing.

Journal of the neurological sciences
BACKGROUND: Patients with ALS often face difficulties expressing emotions due to impairments in facial expression, speech, body language, and cognitive function. This study aimed to develop non-invasive AI tools to detect and quantify emotional respo...

Deep-learning assessment of hippocampal magnetic susceptibility in Alzheimer's disease.

Journal of Alzheimer's disease : JAD
BACKGROUND: Quantitative susceptibility mapping (QSM) is pivotal for analyzing neurodegenerative diseases. However, accurate hippocampal segmentation remains a challenge.

A machine learning-based analysis of nationwide cancer comprehensive genomic profiling data across cancer types to identify features associated with recommendation of genome-matched therapy.

ESMO open
BACKGROUND: The low probability of identifying druggable mutations through comprehensive genomic profiling (CGP) and its financial and time costs hinder its widespread adoption. To enhance the effectiveness and efficiency of cancer precision medicine...

Identification and cognitive function prediction of Alzheimer's disease based on multivariate pattern analysis of hippocampal volumes.

Journal of Alzheimer's disease : JAD
BACKGROUND: Alzheimer's disease (AD) is strongly associated with slowly progressive hippocampal atrophy. Elucidating the relationships between local morphometric changes and disease status for early diagnosis could be aided by machine learning algori...

Graph Convolutional Network for AD and MCI Diagnosis Utilizing Peripheral DNA Methylation: Réseau de neurones en graphes pour le diagnostic de la MA et du TCL à l'aide de la méthylation de l'ADN périphérique.

Canadian journal of psychiatry. Revue canadienne de psychiatrie
OBJECTIVE: Blood DNA methylation (DNAm) alterations have been widely reported in the onset and progression of mild cognitive impairment (MCI) and Alzheimer's disease (AD); however, DNAm is underutilized as a diagnostic biomarker for these diseases. W...

An Application of Machine-Learning-Oriented Radiomics Model in Clear Cell Renal Cell Carcinoma (ccRCC) Early Diagnosis.

British journal of hospital medicine (London, England : 2005)
Clear cell renal cell carcinoma (ccRCC) is a common and aggressive form of kidney cancer, where early diagnosis is crucial for improving prognosis and treatment outcomes. Radiomics, which utilizes machine learning techniques, presents a promising ap...

Time-dependent personalized prognostic analysis by machine learning in biochemical recurrence after radical prostatectomy: a retrospective cohort study.

BMC cancer
BACKGROUND: For biochemical recurrence following radical prostatectomy for prostate cancer, treatments such as radiation therapy and androgen deprivation therapy are administered. To diagnose postoperative recurrence as early as possible and to inter...

Deep learning-accelerated T2WI of the prostate for transition zone lesion evaluation and extraprostatic extension assessment.

Scientific reports
This bicenter retrospective analysis included 162 patients who had undergone prostate biopsy following prebiopsy MRI, excluding those with PCa identified only in the peripheral zone (PZ). DLR T2WI achieved a 69% reduction in scan time relative to TSE...

Social Robots and Sensors for Enhanced Aging at Home: Mixed Methods Study With a Focus on Mobility and Socioeconomic Factors.

JMIR aging
BACKGROUND: Population aging affects society, with a profound impact on daily activities for those of a low socioeconomic status and with motor impairments. Social assistive robots (SARs) and monitoring technologies can improve older adults' well-bei...

Antihypertensive Drug Recommendations for Reducing Arterial Stiffness in Patients With Hypertension: Machine Learning-Based Multicohort (RIGIPREV) Study.

Journal of medical Internet research
BACKGROUND: High systolic blood pressure is one of the leading global risk factors for mortality, contributing significantly to cardiovascular diseases. Despite advances in treatment, a large proportion of patients with hypertension do not achieve op...