AIMC Topic: Aging

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Foundation model-driven distributed learning for enhanced retinal age prediction.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVES: The retinal age gap (RAG) is emerging as a potential biomarker for various diseases of the human body, yet its utility depends on machine learning models capable of accurately predicting biological retinal age from fundus images. However,...

Common and unique brain aging patterns between females and males quantified by large-scale deep learning.

Human brain mapping
There has been extensive evidence that aging affects human brain function. However, there is no complete picture of what brain functional changes are mostly related to normal aging and how aging affects brain function similarly and differently betwee...

External Testing of a Deep Learning Model to Estimate Biologic Age Using Chest Radiographs.

Radiology. Artificial intelligence
Purpose To assess the prognostic value of a deep learning-based chest radiographic age (hereafter, CXR-Age) model in a large external test cohort of Asian individuals. Materials and Methods This single-center, retrospective study included chest radio...

Enhancing Care for Older Adults and Dementia Patients With Large Language Models: Proceedings of the National Institute on Aging-Artificial Intelligence & Technology Collaboratory for Aging Research Symposium.

The journals of gerontology. Series A, Biological sciences and medical sciences
Large Language Models (LLMs) stand on the brink of reshaping the field of aging and dementia care, challenging the one-size-fits-all paradigm with their capacity for precision medicine and individualized treatment strategies. The "Large Pre-Trained M...

Deep Learning-based Brain Age Prediction in Patients With Schizophrenia Spectrum Disorders.

Schizophrenia bulletin
BACKGROUND AND HYPOTHESIS: The brain-predicted age difference (brain-PAD) may serve as a biomarker for neurodegeneration. We investigated the brain-PAD in patients with schizophrenia (SCZ), first-episode schizophrenia spectrum disorders (FE-SSDs), an...

The use of natural language processing for the identification of ageing syndromes including sarcopenia, frailty and falls in electronic healthcare records: a systematic review.

Age and ageing
BACKGROUND: Recording and coding of ageing syndromes in hospital records is known to be suboptimal. Natural Language Processing algorithms may be useful to identify diagnoses in electronic healthcare records to improve the recording and coding of the...

Vascular Age Evaluation Enhanced using Recurrence Plot Analysis and Convolutional Neural Networks: An in-Silico Study.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Aging contributes as a major nonreversible risk factor for cardiovascular disease. This underscores the emergence of Vascular Age (VA) as a promising alternative metric to evaluate an individual's cardiovascular risk and overall health. This study ex...

Deep Learning-Based Vascular Aging Prediction From Retinal Fundus Images.

Translational vision science & technology
PURPOSE: The purpose of this study was to establish and validate a deep learning model to screen vascular aging using retinal fundus images. Although vascular aging is considered a novel cardiovascular risk factor, the assessment methods are currentl...

Machine learning in time-lapse imaging to differentiate embryos from young vs old mice†.

Biology of reproduction
Time-lapse microscopy for embryos is a non-invasive technology used to characterize early embryo development. This study employs time-lapse microscopy and machine learning to elucidate changes in embryonic growth kinetics with maternal aging. We anal...