AIMC Topic: Animals

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Intelligent in-cell electrophysiology: Reconstructing intracellular action potentials using a physics-informed deep learning model trained on nanoelectrode array recordings.

Nature communications
Intracellular electrophysiology is essential in neuroscience, cardiology, and pharmacology for studying cells' electrical properties. Traditional methods like patch-clamp are precise but low-throughput and invasive. Nanoelectrode Arrays (NEAs) offer ...

Physalis Calyx seu Fructus relieves chicken intestinal damage to heat via improving the antioxidant ability.

Frontiers in immunology
Heat-stress-induced oxidative and inflammatory responses were important factors contributing to chicken intestinal damage. The purpose of this study was based on the antioxidant and anti-inflammatory activities of Physalis Calyx seu Fructus (Jin Deng...

Foot trajectory as a key factor for diverse gait patterns in quadruped robot locomotion.

Scientific reports
Four-legged robots are becoming increasingly pivotal in navigating challenging environments, such as construction sites and disaster zones. While substantial progress in robotic mobility has been achieved using reinforcement learning techniques, quad...

Opioid growth factor receptor overexpression exerts anti-hepatocellular carcinoma effects by activating P16 and P21 to inhibit proliferation and migration of HepG2 cells.

Folia histochemica et cytobiologica
INTRODUCTION: Hepatocellular carcinoma (HCC) is the sixth most common type of cancer and the second leading cause of cancer death worldwide [19]. Opioid growth factor (OGF) has been shown to exhibit antitumour potential, binding to OGF receptor (OGFr...

Machine Learning-Assisted High-Throughput Screening of Nanozymes for Ulcerative Colitis.

Advanced materials (Deerfield Beach, Fla.)
Ulcerative colitis (UC) is a chronic gastrointestinal inflammatory disorder with rising prevalence. Due to the recurrent and difficult-to-treat nature of UC symptoms, current pharmacological treatments fail to meet patients' expectations. This study ...

Exploring the impact of land use on bird diversity in high-density urban areas using explainable machine learning models.

Journal of environmental management
Amid rapid urbanization, land use shifts in cities globally have profound effects on ecosystems and biodiversity. Birds, as a crucial component of urban biodiversity, are highly sensitive to environmental changes and often serve as indicator species ...

'Applications of machine learning in liposomal formulation and development'.

Pharmaceutical development and technology
Machine learning (ML) has emerged as a transformative tool in drug delivery, particularly in the design and optimization of liposomal formulations. This review focuses on the intersection of ML and liposomal technology, highlighting how advanced algo...

Quantitative prediction of toxicological points of departure using two-stage machine learning models: A new approach methodology (NAM) for chemical risk assessment.

Journal of hazardous materials
Point of departure (POD) is a concept used in risk assessment to calculate the reference dose of exposure that is likely to have no appreciable risk on health. POD can be directly utilized from no observed adverse effect levels (NOAEL) which is the d...

Cooking loss estimation of semispinalis capitis muscle of pork butt using a deep neural network on hyperspectral data.

Meat science
This study evaluated the performance of a deep-learning-based model that predicted cooking loss in the semispinalis capitis (SC) muscle of pork butts using hyperspectral images captured 24 h postmortem. To overcome low-scale samples, 70 pork butts we...