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Identifying disease progression biomarkers in metabolic associated steatotic liver disease (MASLD) through weighted gene co-expression network analysis and machine learning.
Journal of translational medicine
Apr 24, 2025
BACKGROUND: Metabolic Associated Steatotic Liver Disease (MASLD), encompassing conditions simple liver steatosis (MAFL) and metabolic associated steatohepatitis (MASH), is the most prevalent chronic liver disease. Currently, the management of MASLD i...
Identification of pivotal genes and regulatory networks associated with SAH based on multi-omics analysis and machine learning.
Scientific reports
Apr 24, 2025
Subarachnoid hemorrhage (SAH) is a disease with high mortality and morbidity, and its pathophysiology is complex but poorly understood. To investigate the potential therapeutic targets post-SAH, the SAH-related feature genes were screened by the comb...
Identification and verification of mitochondria-related genes biomarkers associated with immune infiltration for COPD using WGCNA and machine learning algorithms.
Scientific reports
Apr 24, 2025
Mitochondrial dysfunction plays a pivotal role in the pathogenesis of chronic obstructive pulmonary disease (COPD). This study combines bioinformatics analysis with machine learning to elucidate potential key mitochondrial-related genes associated wi...
An interpretable approach to estimate the self-motion in fish-like robots using mode decomposition analysis.
Nature communications
Apr 24, 2025
The artificial lateral line system, composed of velocity and pressure sensors, is the sensing system for fish-like robots by mimicking the lateral line system of aquatic organisms. However, accurately estimating the self-motion of the fish-like robot...
Role of artificial intelligence in advancing immunology.
Immunologic research
Apr 24, 2025
Artificial intelligence (AI) has revolutionized various biomedical fields, particularly immunology, by enhancing vaccine development, immunotherapies, and allergy treatments. AI helps identify potential vaccine candidates and predict how the body rea...
Definer: A computational method for accurate identification of RNA pseudouridine sites based on deep learning.
PloS one
Apr 24, 2025
Pseudouridine is an important modification site, which is widely present in a variety of non-coding RNAs and is involved in a variety of important biological processes. Studies have shown that pseudouridine is important in many biological functions s...
Integrating machine learning and neural networks for new diagnostic approaches to idiopathic pulmonary fibrosis and immune infiltration research.
PloS one
Apr 24, 2025
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease with a fatal outcome, known for its rapid progression and unpredictable clinical course. However, the tools available for diagnosing and treating IPF are quite limited. T...
Pruning Sparse Tensor Neural Networks Enables Deep Learning for 3D Ultrasound Localization Microscopy.
IEEE transactions on image processing : a publication of the IEEE Signal Processing Society
Apr 24, 2025
Ultrasound Localization Microscopy (ULM) is a non-invasive technique that allows for the imaging of micro-vessels in vivo, at depth and with a resolution on the order of ten microns. ULM is based on the sub-resolution localization of individual micro...
Decoding the crossroads of aging and cancer through single-cell analysis: Implications for precision oncology.
International journal of cancer
Apr 23, 2025
Single-cell analysis is a transformative approach to understanding cellular heterogeneity in aging and cancer, interconnected processes driven by mechanisms like senescence and immune modulation. This review explores how aging influences cancer initi...
Linking cellular-level phenomena to brain architecture: the case of spiking cerebellar controllers.
Neural networks : the official journal of the International Neural Network Society
Apr 23, 2025
Linking cellular-level phenomena to brain architecture and behavior is a holy grail for theoretical and computational neuroscience. Advances in neuroinformatics have recently allowed scientists to embed spiking neural networks of the cerebellum with ...
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