AIMC Topic: Animals

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Antibiogram use on dairy cattle for bovine respiratory disease: Factors associated with bacterial pathogen identification and prediction of bacterial recovery using machine learning.

Journal of dairy science
Effective isolation of bacterial pathogens for bovine respiratory disease (BRD) is a critical step for accurate diagnosis of the agent associated with this disease on the dairy. Limited information is available on factors associated with herd-level b...

Milk lipidome alterations in first-lactation dairy cows with lameness: A biomarker identification approach using untargeted lipidomics and machine learning.

Journal of dairy science
Lameness, defined as an impaired gait, impacts cow welfare and performance, compromising future health and production, and increasing culling risk. Untargeted milk lipidomics, together with the use of machine learning methods, have shown promise in i...

ShenJiaoLingCao decoction ameliorates cyclophosphamide-induced splenic injury and immunosuppression via the inhibition of MEK/ERK signaling pathway activity and modulation of amino acid metabolism.

Journal of ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE: ShenJiaoLingCao Decoction (SJLCD) is derived from the classic Chinese medicine prescription, which consists of ten kinds of herbs. In China, SJLCD has been used as an immunomodulator in clinical practice for more than ...

Design and Synthesis of Magnolol Derivatives Using Integrated CNNs and Pharmacophore Approaches for Enhanced Parasiticidal Activity in Aquaculture.

Journal of agricultural and food chemistry
Aquaculture is a rapidly growing sector of global food production, playing a vital role in poverty alleviation, food security, and income generation. However, it faces substantial challenges, particularly due to infections caused by the protozoan , l...

Multiclass CNN Approach for Automatic Classification of Dolphin Vocalizations.

Sensors (Basel, Switzerland)
Monitoring dolphins in the open sea is essential for understanding their behavior and the impact of human activities on the marine ecosystems. Passive Acoustic Monitoring (PAM) is a non-invasive technique for tracking dolphins, providing continuous d...

Sticking the landing: Insect-inspired strategies for safely landing flapping-wing aerial microrobots.

Science robotics
For flying insects, the transition from flight to surface locomotion requires effective touchdown maneuvers that allow stable landings on a variety of surfaces. Landing behaviors of insects are diverse, with some using more controlled flight approach...

Integration of machine learning and experimental validation reveals new lipid-lowering drug candidates.

Acta pharmacologica Sinica
Hyperlipidemia, a major risk factor for cardiovascular diseases, is associated with limitations in clinical lipid-lowering medications. Drug repurposing strategies expedite the research process and mitigate development costs, offering an innovative a...

High-resolution dynamic imaging of chromatin DNA communication using Oligo-LiveFISH.

Cell
Three-dimensional (3D) genome dynamics are crucial for cellular functions and disease. However, real-time, live-cell DNA visualization remains challenging, as existing methods are often confined to repetitive regions, suffer from low resolution, or r...

Microbiome determinants of productivity in aquaculture of whiteleg shrimp.

Applied and environmental microbiology
UNLABELLED: Aquaculture holds immense promise for addressing the food needs of our growing global population. Yet, a quantitative understanding of the factors that control its efficiency and productivity has remained elusive. In this study, we addres...

Rapid diagnosis of membranous nephropathy based on kidney tissue Raman spectroscopy and deep learning.

Scientific reports
Membranous nephropathy (MN) is one of the most common glomerular diseases. Although the diagnostic method based on serum PLA2R antibodies has gradually been applied in clinical practice, only 52-86% of PLA2R-associated MN patients show positive anti-...