The Gene Ontology resource (GO; http://geneontology.org) provides structured, computable knowledge regarding the functions of genes and gene products. Founded in 1998, GO has become widely adopted in the life sciences, and its contents are under cont...
Virulence factors (VFs) are molecules that allow microbial pathogens to overcome host defense mechanisms and cause disease in a host. It is critical to study VFs for better understanding microbial pathogenesis and host defense mechanisms. Victors (ht...
Alternatives to laboratory animals : ATLA
Jan 1, 2019
Safety and efficacy testing is a crucial part of the drug development process, and several different methods are used to obtain the necessary data (e.g. testing, animal trials and clinical trials). Our group has been investigating the potential of m...
Advances in experimental medicine and biology
Jan 1, 2019
Globally, the world population is ageing, which increases the prevalence of non-communicable diseases that affect patients both physically and psychologically, such as is the case of dementia. Consequently, there is a greater demand for the healthcar...
The restoration of voluntary muscle activity in posttraumatic paraplegia in both animal experiments and other clinical applications requires reproducibility of a technically-demanding microsurgical procedure, limited by physicians' understanding of B...
The type of host that a virus can infect, referred to as host specificity or tropism, influences infectivity and thus is important for disease diagnosis, epidemic response, and prevention. Advances in DNA sequencing technology have enabled rapid meta...
Acta of bioengineering and biomechanics
Jan 1, 2019
PURPOSE: Recent innovations in robotics have enabled the development of automatic bone drilling tools which allows surgeons to improve the precision of their surgical operations. However, these tools still lack valuable tactile information about the ...
Journal of X-ray science and technology
Jan 1, 2019
OBJECTIVE: To develop and test a novel method for automatic quantification of hepatic steatosis in histologic images based on the deep learning scheme designed to predict the fat ratio directly, which aims to improve accuracy in diagnosis of non-alco...
Advances in experimental medicine and biology
Jan 1, 2019
Brain-machine interface (BMI) provides a bidirectional pathway between the brain and external facilities. The machine-to-brain pathway makes it possible to send artificial information back into the biological brain, interfering neural activities and ...
In recent years, the successful implementation of human genome project has made people realize that genetic, environmental and lifestyle factors should be combined together to study cancer due to the complexity and various forms of the disease. The i...
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