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Anti-Inflammatory Agents

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Elettaria cardamomum essential oil; immunomodulatory, antioxidant, and anti-inflammatory effects for controlling acute Toxoplasma gondii infection.

Tropical biomedicine
The present study was conducted to investigate the immunomodulatory and anti-inflammatory effects of Elettaria cardamomum essential oil (ECEO) for the control of acute Toxoplasma gondii infection. The effect of ECEO on T. gondii tachyzoites was measu...

Biological activities of crude leaf extract and fractions of Scutellaria sibthorpii (Benth.) Halácsy: An endemic plant of North-Cyprus.

Pakistan journal of pharmaceutical sciences
Scutellaria sibthorpii is used in treatment of bacterial infections, pains and inflammations. The leaf was extracted by maceration and then partitioned with hexane, ethyl acetate and n-butanol. The extract was screened for phytochemicals. The antioxi...

Pharmacokinetics of panduratin A following oral administration of a Boesenbergia pandurata extract to rats.

Journal of food and drug analysis
Boesenbergia pandurata and its major active ingredient, panduratin A (PAN), exhibit antibacterial, anti-oxidant, anti-inflammatory, and anti-obesity effects. We explored the time course of the plasma and tissue (in the major organs, gums and skin) co...

Protection against ulcerative colitis and colorectal cancer by evodiamine via anti‑inflammatory effects.

Molecular medicine reports
Evodiamine (Evo) is an alkaloid that can be extracted from the berry fruit and has been reported to exert various pharmacological effects, such as antidiarrheal, antiemetic and antiulcer effects. , the potential effects of Evo were investigated in a...

Solubility Optimization of Loxoprofen as a Nonsteroidal Anti-Inflammatory Drug: Statistical Modeling and Optimization.

Molecules (Basel, Switzerland)
Industrial-based application of supercritical CO (SCCO) has emerged as a promising technology in numerous scientific fields due to offering brilliant advantages, such as simplicity of application, eco-friendliness, and high performance. Loxoprofen so...

Anti-inflammatory therapy enables robot-actuated regeneration of aged muscle.

Science robotics
Robot-actuated mechanical loading (ML)-based therapies ("mechanotherapies") can promote regeneration after severe skeletal muscle injury, but the effectiveness of such approaches during aging is unknown and may be influenced by age-associated decline...

IF-AIP: A machine learning method for the identification of anti-inflammatory peptides using multi-feature fusion strategy.

Computers in biology and medicine
BACKGROUND: The most commonly used therapy currently for inflammatory and autoimmune diseases is nonspecific anti-inflammatory drugs, which have various hazardous side effects. Recently, some anti-inflammatory peptides (AIPs) have been found to be a ...

High-Content Image-Based Screening and Deep Learning for the Detection of Anti-Inflammatory Drug Leads.

Chembiochem : a European journal of chemical biology
We developed a high-content image-based screen that utilizes the pro-inflammatory stimulus lipopolysaccharide (LPS) and murine macrophages (RAW264.7) with the goal of enabling the identification of novel anti-inflammatory lead compounds. We screened ...

Predicting Anti-inflammatory Peptides by Ensemble Machine Learning and Deep Learning.

Journal of chemical information and modeling
Inflammation is a biological response to harmful stimuli, aiding in the maintenance of tissue homeostasis. However, excessive or persistent inflammation can precipitate a myriad of pathological conditions. Although current treatments such as NSAIDs, ...