Identification of bioactive milk peptides could improve food technology through improved selection of food supplements with a focus on antihypertensive properties. We hypothesized that angiotensin I-converting enzyme (ACE) inhibitory activities of mi...
BACKGROUND: The Drug Ontology (DrOn) is an OWL2-based representation of drug products and their ingredients, mechanisms of action, strengths, and dose forms. We originally created DrOn for use cases in comparative effectiveness research, primarily to...
Two accurate and sensitive methods were developed and validated for the simultaneous determination of amlodipine (AML), valsartan (VAL), and hydrochlorothiazide (HCT) in their ternary mixture. The first method is a novel simple algorithm capable of e...
Hypertension continues to be the leading modifiable risk factor for mortality globally, contributing significantly to cardiovascular disease. The American Heart Association (AHA) 2017 Hypertension Guidelines define hypertension as blood pressure (BP)...
BACKGROUND: Transformer-based neural networks excel in modelling high-dimensional, time-series data with complex dependencies. This proof-of-concept study applies a transformer-X-learner framework to estimate treatment effects using real-world data, ...
Hypertension remains a major global health challenge, contributing to significant morbidity and mortality. Advances in artificial intelligence (AI) and machine learning (ML) are transforming hypertension care by enhancing blood pressure (BP) measurem...
Luminescence : the journal of biological and chemical luminescence
May 1, 2025
In this study, we present a direct, sensitive, and green spectrofluorimetric approach for simultaneous measurement of bisoprolol fumarate (BSL) and amlodipine besylate (AMD) in their tablets and plasma. This approach measures the synchronized fluores...
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Feb 1, 2025
OBJECTIVE: To enhance the understanding of identifying personalized pharmacotherapy options in Traditional Chinese Medicine (TCM), and further support the registration of new TCM drugs.
Hypertension, often known as high blood pressure, is a major concern to millions of individuals globally. Recent studies have demonstrated the significant efficacy of naturally derived peptides in reducing blood pressure. Hypertension is one of the r...
Translational vision science & technology
Jun 3, 2024
PURPOSE: To develop machine learning (ML) and deep learning (DL) models to predict glaucoma surgical outcomes, including postoperative intraocular pressure, use of ocular antihypertensive medications, and need for repeat surgery.
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