AIMC Topic: Antihypertensive Agents
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Novel Pure Component Contribution Algorithm (PCCA) and UHPLC Methods for Separation and Quantification of Amlodipine, Valsartan, and Hydrochlorothiazide in Ternary Mixture.
Journal of AOAC International
Dec 21, 2016
Two accurate and sensitive methods were developed and validated for the simultaneous determination of amlodipine (AML), valsartan (VAL), and hydrochlorothiazide (HCT) in their ternary mixture. The first method is a novel simple algorithm capable of e...
A Transformer-Based Framework for Counterfactual Estimation of Antihypertensive Treatment Effect on COVID-19 Infection Risk - A Proof-of-Concept Study.
American journal of hypertension
Jul 15, 2025
BACKGROUND: Transformer-based neural networks excel in modelling high-dimensional, time-series data with complex dependencies. This proof-of-concept study applies a transformer-X-learner framework to estimate treatment effects using real-world data, ...
Artificial Intelligence to Improve Blood Pressure Control: A State-of-the-Art Review.
American journal of hypertension
Jul 15, 2025
Hypertension remains a major global health challenge, contributing to significant morbidity and mortality. Advances in artificial intelligence (AI) and machine learning (ML) are transforming hypertension care by enhancing blood pressure (BP) measurem...
A Green Synchronous Fluorescence Analysis Approach for Simultaneous Determination of the Co-formulated Antihypertensives, Bisoprolol, and Amlodipine. Application to Plasma Samples, Market Formulations, Content Uniformity Test, and Greenness Evaluation.
Luminescence : the journal of biological and chemical luminescence
May 1, 2025
In this study, we present a direct, sensitive, and green spectrofluorimetric approach for simultaneous measurement of bisoprolol fumarate (BSL) and amlodipine besylate (AMD) in their tablets and plasma. This approach measures the synchronized fluores...
Integrating machine learning and human use experience to identify personalized pharmacotherapy in Traditional Chinese Medicine: a case study on resistant hypertension.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Feb 1, 2025
OBJECTIVE: To enhance the understanding of identifying personalized pharmacotherapy options in Traditional Chinese Medicine (TCM), and further support the registration of new TCM drugs.
StackAHTPs: An explainable antihypertensive peptides identifier based on heterogeneous features and stacked learning approach.
IET systems biology
Jan 1, 2025
Hypertension, often known as high blood pressure, is a major concern to millions of individuals globally. Recent studies have demonstrated the significant efficacy of naturally derived peptides in reducing blood pressure. Hypertension is one of the r...
Predicting Glaucoma Surgical Outcomes Using Neural Networks and Machine Learning on Electronic Health Records.
Translational vision science & technology
Jun 3, 2024
PURPOSE: To develop machine learning (ML) and deep learning (DL) models to predict glaucoma surgical outcomes, including postoperative intraocular pressure, use of ocular antihypertensive medications, and need for repeat surgery.
Better Blood Pressure Control for Stroke Patients in the ICU: A Deep Reinforcement Learning with Supervised Guidance Approach for Adaptive Infusion Rate Tuning.
AMIA ... Annual Symposium proceedings. AMIA Symposium
Jan 1, 2024
Blood pressure variability (BPV) plays a critical role in vascular diseases, particularly in acute ischemic stroke patients in intensive care units (ICUs), where higher BPV correlates with increased mortality rates. Current interventions lack effecti...
Antihypertensive Activity of Sauromatum guttatum Mediated by Vasorelaxation and Myocardial Depressant Effects.
Arquivos brasileiros de cardiologia
Dec 1, 2021
BACKGROUND: Sauromatum guttatum (S. guttatum) is used in the treatment of blood disorders and reportedly has a spasmolytic activity through Ca2+ channel inhibition.
Ex-vivo antihypertensive and calcium channel blocking activity of Androsace foliosa n-hexane leaves fraction on isolated rabbit aorta.
Pakistan journal of pharmaceutical sciences
Nov 1, 2019
Hypertension is persistent elevation in blood pressure for 3-4 weeks. Estimated global prevalence of hypertension suggested that by the Year 2025 (29%) of adult worldwide are suffering from hypertension (1.56 billion). Hypertension complications are ...
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