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Prediction of the risk of mortality in older patients with coronavirus disease 2019 using blood markers and machine learning.

Frontiers in immunology
INTRODUCTION: The mortality rate among older people infected with severe acute respiratory syndrome coronavirus 2 is alarmingly high. This study aimed to explore the predictive value of a novel model for assessing the risk of death in this vulnerable...

Explainable machine learning for early prediction of sepsis in traumatic brain injury: A discovery and validation study.

PloS one
BACKGROUND: People with traumatic brain injury (TBI) are at high risk for infection and sepsis. The aim of the study was to develop and validate an explainable machine learning(ML) model based on clinical features for early prediction of the risk of ...

Machine-Learning Application for Predicting Metabolic Dysfunction-Associated Steatotic Liver Disease Using Laboratory and Body Composition Indicators.

Archives of Iranian medicine
BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a significant global health burden without established curative therapies. Early detection and preventive strategies are crucial for effective MASLD management. T...

Machine learning for stroke in heart failure with reduced ejection fraction but without atrial fibrillation: A post-hoc analysis of the WARCEF trial.

European journal of clinical investigation
BACKGROUND: The prediction of ischaemic stroke in patients with heart failure with reduced ejection fraction (HFrEF) but without atrial fibrillation (AF) remains challenging. Our aim was to evaluate the performance of machine learning (ML) in identif...

The use of 4D data-independent acquisition-based proteomic analysis and machine learning to reveal potential biomarkers for stress levels.

Journal of bioinformatics and computational biology
Research suggests that individuals who experience prolonged exposure to stress may be at higher risk for developing psychological stress disorders. Currently, psychological stress is primarily evaluated by professional physicians using rating scales,...

Predicting stroke severity of patients using interpretable machine learning algorithms.

European journal of medical research
BACKGROUND: Stroke is a significant global health concern, ranking as the second leading cause of death and placing a substantial financial burden on healthcare systems, particularly in low- and middle-income countries. Timely evaluation of stroke se...

Detection of breast cancer using machine learning on time-series diffuse optical transillumination data.

Journal of biomedical optics
SIGNIFICANCE: Optical mammography as a promising tool for cancer diagnosis has largely fallen behind expectations. Modern machine learning (ML) methods offer ways to improve cancer detection in diffuse optical transmission data.

Machine learning for outcome prediction in patients with non-valvular atrial fibrillation from the GLORIA-AF registry.

Scientific reports
Clinical risk scores that predict outcomes in patients with atrial fibrillation (AF) have modest predictive value. Machine learning (ML) may achieve greater results when predicting adverse outcomes in patients with recently diagnosed AF. Several ML m...

An improved AlexNet deep learning method for limb tumor cancer prediction and detection.

Biomedical physics & engineering express
Synovial sarcoma (SS) is a rare cancer that forms in soft tissues around joints, and early detection is crucial for improving patient survival rates. This study introduces a convolutional neural network (CNN) using an improved AlexNet deep learning c...

Unraveling Uncertainty: The Impact of Biological and Analytical Variation on the Prediction Uncertainty of Categorical Prediction Models.

The journal of applied laboratory medicine
BACKGROUND: Interest in prediction models, including machine learning (ML) models, based on laboratory data has increased tremendously. Uncertainty in laboratory measurements and predictions based on such data are inherently intertwined. This study d...