BACKGROUND: Deep learning (DL) demonstrates high sensitivity but low specificity in lung cancer (LC) detection during CT screening, and the seven Tumor-associated antigens autoantibodies (7-TAAbs), known for its high specificity in LC, was employed t...
The diagnostic delay in celiac disease (CD) is currently a burden for individual and society. Biochemical tests may be used in risk-identification of CD to reduce the diagnostic delay, and we aimed to explore prediction models for CD antibody seropos...
OBJECTIVES: To develop and validate a machine learning (ML) model to differentiate malignant from benign thyroid nodules (TNs) based on the routine data and provide diagnostic assistance for medical professionals.
BACKGROUND: Autoantibodies represent promising diagnostic blood-based biomarkers that may be generated prior to the first clinically detectable signs of cancers. In present study, we aimed to identify a novel optimized autoantibody panel with high di...
In our study, we aim to predict the antibody serostatus of patients with suspected autoimmune encephalitis (AE) using machine learning based on pre-contrast T2-weighted MR images acquired at symptom onset. A confirmation of seropositivity is of great...
BACKGROUND: Primary Sjogren's syndrome (pSS) and autoimmune thyroiditis (AIT) share overlapping genetic and immunological profiles. This retrospective study evaluates the efficacy of machine learning algorithms, with a focus on the Random Forest Clas...
Identifying which patients should undergo serologic screening for celiac disease (CD) may help diagnose patients who otherwise often experience diagnostic delays or remain undiagnosed. Using anonymized outpatient data from the electronic medical reco...
Breast cancer (BC) has become a global health problem, ranking first in incidence and fifth in mortality in women around the world. Although there are some diagnostic methods for the disease, these are not sufficiently effective and are invasive. In ...
BACKGROUND: Primary Sjögren's syndrome (pSS) is a chronic systemic autoimmune disease characterized by lymphocyte infiltration of the exocrine glands. Interferon-stimulated genes (ISGs) are often upregulated in patients with pSS, and anti-SSA/Ro 60 a...
Disrupted cytokine networks and autoantibodies play an important role in the pathogenesis of systemic lupus erythematosus. However, conflicting reports and non-reproducibility have hindered progress regarding the translational potential of cytokines ...
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