Based on morphology it is often challenging to distinguish between the many different soft tissue sarcoma subtypes. Moreover, outcome of disease is highly variable even between patients with the same disease. Machine learning on transcriptome sequenc...
AIM: Pancreatic cancer is one of the worst malignant tumors in prognosis. Therefore, to reduce the mortality rate of pancreatic cancer, early diagnosis and prompt treatment are particularly important.
IEEE transactions on bio-medical engineering
Feb 13, 2019
Accurate profiling of tumors using immunohistochemistry (IHC) is essential in cancer diagnosis. The inferences drawn from IHC-stained images depend to a great extent on the quality of immunostaining, which is in turn affected strongly by assay parame...
IEEE/ACM transactions on computational biology and bioinformatics
Feb 4, 2019
Variable selection has attracted more attention in big data and machine learning fields. In high dimensional data analysis, many relevant variables or variable groups are widely found. For example, people pay more interests to biological pathway or r...
Due to the exponential growth of computational algorithms, artificial intelligence (AI) methods are poised to improve the precision of diagnostic and therapeutic methods in medicine. The field of radiomics in neuro-oncology has been and will likely c...
Increased urinary acetylated polyamines (APs) are reported as cancer biomarkers in many studies. N,N-diacetylspermine has been proposed as a biomarker indicative of different cancers in urine and plasma. N-Acetylspermine has previously been found to ...
BACKGROUND: Breast cancer (BC) is one of the most prevalent and reported cancers among Saudi women. Detection of BC in the early invasive stage (stages I, II) has an advantage in treating patients over detection in the late invasive stage (stages III...
BACKGROUND: Predicting prognosis in patients from large-scale genomic data is a fundamentally challenging problem in genomic medicine. However, the prognosis still remains poor in many diseases. The poor prognosis may be caused by high complexity of ...
International journal of clinical oncology
Dec 12, 2018
In Japan, the National Cancer Center and university hospitals have initiated next-generation sequencing-based in vitro diagnostic testing for cancer patients as a method of clinical sequencing. Based on the molecular alterations detected, physicians ...
BACKGROUND: Identification of differentially expressed genes, i.e., genes whose transcript abundance level differs across different biological or physiological conditions, was indeed a challenging task. However, the inception of transcriptome sequenc...
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