BACKGROUND: With the rapid development of digital biomarkers in Parkinson disease (PD) research, it has become increasingly important to explore the current research trends and key areas of focus.
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common reproductive and metabolic disorder in the reproductive-age women. The international evidence-based guideline for the assessment and management of PCOS 2023 now suggests raising the follicle nu...
Dementia spectrum disorders, characterized by progressive cognitive decline, pose a significant global health burden. Early screening and diagnosis are essential for timely and accurate treatment, improving patient outcomes and quality of life. This ...
BACKGROUND: Infection by the SARS-CoV-2 virus can cause coronavirus disease 2019 (COVID-19) and can also exacerbate the symptoms of Kawasaki disease (KD), an acute vasculitis that mostly affects children. This study used bioinformatics and machine le...
Understanding the molecular underpinnings of CAD is essential for developing effective therapeutic strategies. This study aims to identify and analyze differentially expressed hub biomarkers in the peripheral blood of CAD patients. Based on RNA-seq d...
BACKGROUND: Chronic obstructive pulmonary disease (COPD) and type 2 diabetes mellitus (T2DM) are on the rise. While there is evidence of a link between the two diseases, the pathophysiological mechanisms they share are not fully understood.
To study the differences in the urine metabolome between pediatric patients with severe Mycoplasma pneumoniae pneumonia (SMPP) and those with general Mycoplasma pneumoniae pneumonia (GMPP) via non-targeted metabolomics method, and potential biomarker...
International journal of molecular sciences
May 15, 2025
Osteoarthritis (OA) is a prevalent and disabling chronic disease, with knee OA being the most common form, affecting approximately 73% of individuals over 55 years. Traditional clinical assessments often fail to predict knee structural progression ac...
International journal of molecular sciences
May 15, 2025
Despite several years passing since the COVID-19 pandemic was declared, challenges remain in understanding the factors that can predict the severity of COVID-19 disease and complications of SARS-CoV-2 infection. While many large-scale multi-omic data...
International journal of molecular sciences
May 15, 2025
Glaucoma is an age-related neurodegenerative disease characterized by progressive optic nerve damage. Accelerated biological aging, assessed using predicted age derived from fundus images, may serve as a biomarker for glaucoma progression. This study...
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