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Biomarkers

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Assessing donor kidney function: the role of CIRBP in predicting delayed graft function post-transplant.

Frontiers in immunology
INTRODUCTION: Delayed graft function (DGF) shortens the survival time of transplanted kidneys and increases the risk of rejection. Current methods are inadequate in predicting DGF. More precise tools are required to assess kidney suitability for tran...

Role of Artificial Intelligence in Identifying Vital Biomarkers with Greater Precision in Emergency Departments During Emerging Pandemics.

International journal of molecular sciences
The COVID-19 pandemic has accelerated advances in molecular biology and virology, enabling the identification of key biomarkers to differentiate between severe and mild cases. Furthermore, the use of artificial intelligence (AI) and machine learning ...

Deep learning and generative artificial intelligence in aging research and healthy longevity medicine.

Aging
With the global population aging at an unprecedented rate, there is a need to extend healthy productive life span. This review examines how Deep Learning (DL) and Generative Artificial Intelligence (GenAI) are used in biomarker discovery, deep aging ...

Development and Validation of a Machine Learning Method Using Vocal Biomarkers for Identifying Frailty in Community-Dwelling Older Adults: Cross-Sectional Study.

JMIR medical informatics
BACKGROUND: The two most commonly used methods to identify frailty are the frailty phenotype and the frailty index. However, both methods have limitations in clinical application. In addition, methods for measuring frailty have not yet been standardi...

Kernel representation-based End-to-End network-enabled decoding strategy for precise and medical diagnosis.

Journal of hazardous materials
Artificial intelligence-assisted imaging biosensors have attracted increasing attention due to their flexibility, allowing for the digital image analysis and quantification of biomarkers. While deep learning methods have led to advancements in biomar...

Identifying semaphorin 3C as a biomarker for sarcopenia and coronary artery disease via bioinformatics and machine learning.

Archives of gerontology and geriatrics
OBJECTIVE: Sarcopenia not only affects patients' quality of life but also may exacerbate the pathological processes of coronary artery disease (CAD). This study aimed to identify potential biomarkers to improve the combined diagnosis and treatment of...

Screening of Aβ and phosphorylated tau status in the cerebrospinal fluid through machine learning analysis of portable electroencephalography data.

Scientific reports
Diagnosing Alzheimer's disease (AD) through pathological markers is typically costly and invasive. This study aims to find a noninvasive, cost-effective method using portable electroencephalography (EEG) to detect changes in AD-related biomarkers in ...

Development of a multi-laboratory integrated predictive model for silicosis utilizing machine learning: a retrospective case-control study.

Frontiers in public health
OBJECTIVE: Due to the high global prevalence of silicosis and the ongoing challenges in its diagnosis, this pilot study aims to screen biomarkers from routine blood parameters and develop a multi-biomarker model for its early detection.

Machine learning and multi-omics in precision medicine for ME/CFS.

Journal of translational medicine
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex and multifaceted disorder that defies simplistic characterisation. Traditional approaches to diagnosing and treating ME/CFS have often fallen short due to the condition's hetero...

Identifying effective immune biomarkers in alopecia areata diagnosis based on machine learning methods.

BMC medical informatics and decision making
BACKGROUND: Alopecia areata (AA) is a common non-scarring hair loss disorder associated with autoimmune conditions. However, the pathobiology of AA is not well understood, and there is no targeted therapy available for AA.  METHODS: In this study, di...