AIMC Topic: Biomarkers

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Effects of treatment with chemotherapy and/or tamoxifen on the biomarkers of cardiac injury and oxidative stress in women with breast cancer.

Medicine
There has been an increase in deaths from cardiovascular diseases following breast cancer therapy. Evidence has shown that this outcome is, in part, associated with cardiotoxicity induced by the chemotherapeutic drugs and the increase in oxidative st...

Prediction of persistent post-surgery pain by preoperative cold pain sensitivity: biomarker development with machine-learning-derived analysis.

British journal of anaesthesia
BACKGROUND: To prevent persistent post-surgery pain, early identification of patients at high risk is a clinical need. Supervised machine-learning techniques were used to test how accurately the patients' performance in a preoperatively performed ton...

Salivary Markers for Quantitative Dehydration Estimation During Physical Exercise.

IEEE journal of biomedical and health informatics
Salivary markers have been proposed as noninvasive and easy-to-collect indicators of dehydrations during physical exercise. It has been demonstrated that threshold-based classifications can distinguish dehydrated from euhydrated subjects. However, co...

Metabolite Profiling of ADB-FUBINACA, A New Synthetic Cannabinoid.

Current neuropharmacology
Metabolite profiling of novel psychoactive substances (NPS) is critical for documenting drug consumption. N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (ADB-FUBINACA) is an emerging synthetic cannabinoid whose ...

Adiponectin levels may help assess the clinical repercussions of obesity irrespective of body mass index.

Hormones (Athens, Greece)
OBJECTIVE: Adiponectin is the major product of adipose tissue. The aim of this study was to associate adiponectin levels with adipose tissue and metabolic indices.

Automated cell type discovery and classification through knowledge transfer.

Bioinformatics (Oxford, England)
MOTIVATION: Recent advances in mass cytometry allow simultaneous measurements of up to 50 markers at single-cell resolution. However, the high dimensionality of mass cytometry data introduces computational challenges for automated data analysis and h...

Machine Learning of the Progression of Intermediate Age-Related Macular Degeneration Based on OCT Imaging.

Investigative ophthalmology & visual science
PURPOSE: To develop a data-driven interpretable predictive model of incoming drusen regression as a sign of disease activity and identify optical coherence tomography (OCT) biomarkers associated with its risk in intermediate age-related macular degen...

NT-proBNP Predicts All-Cause Mortality in a Population of Insurance Applicants, Follow-up Analysis and Further Observations.

Journal of insurance medicine (New York, N.Y.)
OBJECTIVE: - Further refine the independent value of NT-proBNP, accounting for the impact of other test results, in predicting all-cause mortality for individual life insurance applicants with and without heart disease.

S100A4 Protein in Inflammatory Bowel Disease: Results of a Single Centre Prospective Study.

Acta medica (Hradec Kralove)
INTRODUCTION: The aim of our study was to assess association of serum S100A4 protein with ulcerative colitis (UC) and Crohn's disease (CD).

[Tetrodotoxin (TTX) Monitoring of Biological Specimens and Toxin Profile in a Food Poisoning Case Caused by the Scavenging Gastropod Nassarius (Alectrion) glans "Kinshibai"].

Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan
In November 2015, a patient presented with symptoms of toxicity after eating whole boiled samples of the scavenging gastropod Nassarius (Alectrion) glans "Kinshibai" in Nagasaki. This food poisoning case was the third recorded in Japan. The case was ...