AIMC Topic: Biomarkers

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Harnessing NLP to investigate biomarker interactions and CVD risks in elderly chronic kidney disease patients.

SLAS technology
Chronic kidney disease (CKD) significantly increases the risk of CVD diseases, particularly among elderly patients. Understanding the interaction between several biomarkers and cardiovascular (CVD) risks is crucial for improving patient outcomes and ...

Brain mapping, biomarker identification and using machine learning method for diagnosis of anxiety during emotional face in preschool children.

Brain research bulletin
BACKGROUND: Due to the importance and the consequences of anxiety, the goals of the current study are brain mapping, biomarker identification and the use of an assessment method for diagnosis of anxiety during emotional face in preschool children.

A machine learning model accurately identifies glycogen storage disease Ia patients based on plasma acylcarnitine profiles.

Orphanet journal of rare diseases
BACKGROUND: Glycogen storage disease (GSD) Ia is an ultra-rare inherited disorder of carbohydrate metabolism. Patients often present in the first months of life with fasting hypoketotic hypoglycemia and hepatomegaly. The diagnosis of GSD Ia relies on...

Comprehensive bioinformatics analysis identifies metabolic and immune-related diagnostic biomarkers shared between diabetes and COPD using multi-omics and machine learning.

Frontiers in endocrinology
BACKGROUND: Diabetes and chronic obstructive pulmonary disease (COPD) are prominent global health challenges, each imposing significant burdens on affected individuals, healthcare systems, and society. However, the specific molecular mechanisms suppo...

Diagnostic and prognostic perspectives of Fabry disease via fiber evanescent wave spectroscopy advanced by machine learning.

Biosensors & bioelectronics
Fabry disease (FD) is a rare disorder resulting from a genetic mutation characterized by the accumulation of sphingolipids in various cells throughout the human body, leading to progressive and irreversible organ damage, particularly in males. Geneti...

A Plasma Proteomics-Based Model for Identifying the Risk of Postpartum Depression Using Machine Learning.

Journal of proteome research
Postpartum depression (PPD) poses significant risks to maternal and infant health, yet proteomic analyses of PPD-risk women remain limited. This study analyzed plasma samples from 30 healthy postpartum women and 30 PPD-risk women using mass spectrome...

Screening of serum biomarkers in patients with PCOS through lipid omics and ensemble machine learning.

PloS one
Polycystic ovary syndrome (PCOS) is a primary endocrine disorder affecting premenopausal women involving metabolic dysregulation. We aimed to screen serum biomarkers in PCOS patients using untargeted lipidomics and ensemble machine learning. Serum fr...