AIMC Topic: Case-Control Studies

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Deep learning-based gene selection in comprehensive gene analysis in pancreatic cancer.

Scientific reports Aug 13, 2021
The selection of genes that are important for obtaining gene expression data is challenging. Here, we developed a deep learning-based feature selection method suitable for gene selection. Our novel deep learning model includes an additional feature-s...
Pancreas Kaplan-Meier Estimate Genes, Neoplasm Aged Male Middle Aged Transcriptome Case-Control Studies Deep Learning Gene Expression Regulation, Neoplastic Pancreatic Neoplasms Carcinoma, Pancreatic Ductal Survival Analysis Humans Female
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Interleukin-37 gene polymorphism and susceptibility to pulmonary tuberculosis among Iraqi patients.

The Indian journal of tuberculosis Aug 12, 2021
BACKGROUND: Control of tuberculosis (TB) depends on a balance between host's immune factors and bacterial evasion strategies. Interleukin-37 (IL-37) is among the immunomodulatory factors that have been proposed to influence susceptibility to tubercul...
Interleukins Humans Iraq Case-Control Studies Tuberculosis, Pulmonary Genetic Predisposition to Disease Polymorphism, Single Nucleotide
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Using normative modelling to detect disease progression in mild cognitive impairment and Alzheimer's disease in a cross-sectional multi-cohort study.

Scientific reports Aug 3, 2021
Normative modelling is an emerging method for quantifying how individuals deviate from the healthy populational pattern. Several machine learning models have been implemented to develop normative models to investigate brain disorders, including regre...
Neural Networks, Computer Machine Learning Brain Female Aged Cognitive Dysfunction Humans Cohort Studies Cross-Sectional Studies Models, Statistical Male Alzheimer Disease Middle Aged Neuroimaging Disease Progression Case-Control Studies
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An automatic screening method for strabismus detection based on image processing.

PloS one Aug 3, 2021
PURPOSE: This study aims to provide an automatic strabismus screening method for people who live in remote areas with poor medical accessibility.
Algorithms Case-Control Studies Image Processing, Computer-Assisted Health Services Accessibility Least-Squares Analysis Humans Mass Screening Strabismus Neural Networks, Computer Face Pupil Electronic Data Processing
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Evaluation of Effect of Curcumin on Psychological State of Patients with Pulmonary Hypertension by Magnetic Resonance Image under Deep Learning.

Contrast media & molecular imaging Jul 26, 2021
This research aimed to evaluate the right ventricular segmentation ability of magnetic resonance imaging (MRI) images based on deep learning and evaluate the influence of curcumin (Cur) on the psychological state of patients with pulmonary hypertensi...
Anti-Inflammatory Agents, Non-Steroidal Algorithms Curcumin Female Hypertension, Pulmonary Deep Learning Humans Adult Aged Depressive Disorder Adolescent Neural Networks, Computer Male Young Adult Follow-Up Studies Middle Aged Magnetic Resonance Imaging Anxiety Disorders Case-Control Studies
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The Value of Convolutional Neural Network-Based Magnetic Resonance Imaging Image Segmentation Algorithm to Guide Targeted Controlled Release of Doxorubicin Nanopreparation.

Contrast media & molecular imaging Jul 26, 2021
There was an investigation of the auxiliary role of convolutional neural network- (CNN-) based magnetic resonance imaging (MRI) image segmentation algorithm in MRI image-guided targeted drug therapy of doxorubicin nanomaterials so that the value of d...
Drug Liberation Humans Delayed-Action Preparations Antibiotics, Antineoplastic Nanoparticle Drug Delivery System Adult Neural Networks, Computer Male Image Processing, Computer-Assisted Algorithms Middle Aged Follow-Up Studies Prognosis Case-Control Studies Magnetic Resonance Imaging Female Liver Neoplasms Doxorubicin Aged
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Diagnosis and Treatment Effect of Convolutional Neural Network-Based Magnetic Resonance Image Features on Severe Stroke and Mental State.

Contrast media & molecular imaging Jul 26, 2021
The purpose of this paper is to explore the impact of magnetic resonance imaging (MRI) image features based on convolutional neural network (CNN) algorithm and conditional random field on the diagnosis and mental state of patients with severe stroke....
Neural Networks, Computer Algorithms Prognosis Female Aged Magnetic Resonance Imaging Case-Control Studies Aged, 80 and over Stroke Humans Cognitive Dysfunction Adult Cerebral Small Vessel Diseases Image Processing, Computer-Assisted Male Follow-Up Studies Middle Aged
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Prediction model for malignant pulmonary nodules based on cfMeDIP-seq and machine learning.

Cancer science Jul 21, 2021
Cell-free methylated DNA immunoprecipitation and high-throughput sequencing (cfMeDIP-seq) is a new bisulfite-free technique, which can detect the whole-genome methylation of blood cell-free DNA (cfDNA). Using this technique, we identified differentia...
Middle Aged Case-Control Studies Lung Neoplasms DNA Methylation Cell-Free Nucleic Acids Multiple Pulmonary Nodules High-Throughput Nucleotide Sequencing Immunoprecipitation Aged Aged, 80 and over Adult Sensitivity and Specificity Male Humans Machine Learning Prognosis Female
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Prediction model for thyrotoxic atrial fibrillation: a retrospective study.

BMC endocrine disorders Jul 11, 2021
BACKGROUND: Thyrotoxic atrial fibrillation (TAF) is a recognized significant complication of hyperthyroidism. Early identification of the individuals predisposed to TAF would improve thyrotoxic patients' management. However, to our knowledge, an inst...
Risk Factors Male Middle Aged Risk Assessment Case-Control Studies Machine Learning Prognosis Retrospective Studies Female Follow-Up Studies Models, Statistical Atrial Fibrillation Hyperthyroidism Heart Rate Humans
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Deep learning prediction of attention-deficit hyperactivity disorder in African Americans by copy number variation.

Experimental biology and medicine (Maywood, N.J.) Jul 7, 2021
Current understanding of the underlying molecular network and mechanism for attention-deficit hyperactivity disorder (ADHD) is lacking and incomplete. Previous studies suggest that genomic structural variations play an important role in the pathogene...
Humans Female Reproducibility of Results Young Adult Male Whole Genome Sequencing Black or African American Case-Control Studies Attention Deficit Disorder with Hyperactivity Deep Learning Genetic Predisposition to Disease DNA Copy Number Variations
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