AIMC Topic: Case-Control Studies
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Application of Computed Tomography Imaging in Diagnosis of Endocrine Nerve of Gastric Cancer and Nursing Intervention Effect.
World neurosurgery
Oct 10, 2020
In this article, some parameters and characteristics of computed tomography (CT) images in patients with gastric cancer are analyzed and the application of CT images in the diagnosis of gastric cancer endocrine nerves and the impact of nursing interv...
Evaluation of a genetic risk score for severity of COVID-19 using human chromosomal-scale length variation.
Human genomics
Oct 9, 2020
INTRODUCTION: The course of COVID-19 varies from asymptomatic to severe in patients. The basis for this range in symptoms is unknown. One possibility is that genetic variation is partly responsible for the highly variable response. We evaluated how w...
Deep neural network improves the estimation of polygenic risk scores for breast cancer.
Journal of human genetics
Oct 2, 2020
Polygenic risk scores (PRS) estimate the genetic risk of an individual for a complex disease based on many genetic variants across the whole genome. In this study, we compared a series of computational models for estimation of breast cancer PRS. A de...
Prediction of incident myocardial infarction using machine learning applied to harmonized electronic health record data.
BMC medical informatics and decision making
Oct 2, 2020
BACKGROUND: With cardiovascular disease increasing, substantial research has focused on the development of prediction tools. We compare deep learning and machine learning models to a baseline logistic regression using only 'known' risk factors in pre...
Combining deep learning with 3D stereophotogrammetry for craniosynostosis diagnosis.
Scientific reports
Sep 18, 2020
Craniosynostosis is a condition in which cranial sutures fuse prematurely, causing problems in normal brain and skull growth in infants. To limit the extent of cosmetic and functional problems, swift diagnosis is needed. The goal of this study is to ...
Prediction Power on Cardiovascular Disease of Neuroimmune Guidance Cues Expression by Peripheral Blood Monocytes Determined by Machine-Learning Methods.
International journal of molecular sciences
Sep 2, 2020
Atherosclerosis is the underlying pathology in a major part of cardiovascular disease, the leading cause of mortality in developed countries. The infiltration of monocytes into the vessel walls of large arteries is a key denominator of atherogenesis,...
Exploring gene-gene interaction in family-based data with an unsupervised machine learning method: EPISFA.
Genetic epidemiology
Sep 1, 2020
Gene-gene interaction (G × G) is thought to fill the gap between the estimated heritability of complex diseases and the limited genetic proportion explained by identified single-nucleotide polymorphisms. The current tools for exploring G × G were oft...
Relation of vitamin D and BsmI variant with temporomandibular diseases in the Turkish population.
The British journal of oral & maxillofacial surgery
Aug 28, 2020
Vitamin D (VD) levels and several variants in the vitamin D receptor (VDR) gene are associated with the occurrence of diseases of the bones and cartilage. The aim of this research was to study and compare the association of the BsmI variant in the VD...
Assessment of and polymorphisms in age-related macular degeneration using classic and machine-learning approaches.
Ophthalmic genetics
Aug 24, 2020
BACKGROUND: and are pivotal genes driving increased risk for age-related macular degeneration (AMD) among several populations. Here, we performed a hospital-based case-control study to evaluate the effects of three single nucleotide polymorphisms (...
Computer Kinesiology: New Diagnostic and Therapeutic Tool for Lower Back Pain Treatment (Pilot Study).
BioMed research international
Aug 24, 2020
The aim of this study was to demonstrate the effectiveness of the diagnostic and therapeutic medical information system Computer Kinesiology in physiotherapy in patients with low back pain who were not responding to conventional therapy. Computer Kin...
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