AIMC Topic: Case-Control Studies

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AI-Driven segmentation and morphogeometric profiling of epicardial adipose tissue in type 2 diabetes.

Cardiovascular diabetology
BACKGROUND: Epicardial adipose tissue (EAT) is associated with cardiometabolic risk in type 2 diabetes (T2D), but its spatial distribution and structural alterations remain understudied. We aim to develop a shape-aware, AI-based method for automated ...

Machine learning and discriminant analysis model for predicting benign and malignant pulmonary nodules.

BMC medical informatics and decision making
BACKGROUND: Pulmonary Nodules (PNs) are a trend considered as the early manifestation of lung cancer. Among them, PNs that remain stable for more than two years or whose pathological results suggest not being lung cancer are considered benign PNs (BP...

EEG microstate analysis in children with prolonged disorders of consciousness.

Scientific reports
Prolonged disorders of consciousness (pDoC) in children lack objective and effective diagnostic methods to assess consciousness states, hindering targeted treatment selection and delaying recovery. It remains unclear whether EEG microstate analysis, ...

Determination of lung cancer exhaled breath biomarkers using machine learning-a new analysis framework.

Scientific reports
Exhaled breath samples of lung cancer patients (LC), tuberculosis (TB) patients and asymptomatic controls (C) were analyzed using gas chromatography-mass spectrometry (GC-MS). Ten volatile organic compounds (VOCs) were identified as possible biomarke...

Raised Leptin and Pappalysin2 cell-free RNAs are the hallmarks of pregnancies complicated by preeclampsia with fetal growth restriction.

Nature communications
Preeclampsia (PE) and fetal growth restriction (FGR) complicate 5-10% of pregnancies and are major causes of maternal and fetal morbidity and mortality. Here we demonstrate that measuring circulating cell-free RNAs (cfRNAs) from maternal plasma can a...

Artificial intelligence-based diabetes risk prediction from longitudinal DXA bone measurements.

Scientific reports
Diabetes mellitus (DM) is a serious global health concern that poses a significant threat to human life. Beyond its direct impact, diabetes substantially increases the risk of developing severe complications such as hypertension, cardiovascular disea...

Finger drawing on smartphone screens enables early Parkinson's disease detection through hybrid 1D-CNN and BiGRU deep learning architecture.

PloS one
BACKGROUND: Parkinson's disease (PD), a progressive neurodegenerative disorder prevalent in aging populations, manifests clinically through characteristic motor impairments including bradykinesia, rigidity, and resting tremor. Early detection and tim...

Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech.

Translational psychiatry
Psychosis poses substantial social and healthcare burdens. The analysis of speech is a promising approach for the diagnosis and monitoring of psychosis, capturing symptoms like thought disorder and flattened affect. Recent advancements in Natural Lan...

Identification and validation of parthanatos-related genes in end-stage renal disease.

Renal failure
BACKGROUND: End-Stage Renal Disease (ESRD) is a severe chronic kidney disease with a rising global incidence, often accompanied by various complications, severely impacting patients' quality of life. Parthanatos plays a crucial role in the pathogenes...

Prediction of suicide using web based voice recordings analyzed by artificial intelligence.

Scientific reports
The integration of machine learning (ML) and deep learning models in suicide risk assessment has advanced significantly in recent years. In this study, we utilized ML in a case-control design, we predicted completed suicides using publicly available,...