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Cerebral Cortex

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Deep Artificial Neural Networks Reveal a Distributed Cortical Network Encoding Propositional Sentence-Level Meaning.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Understanding how and where in the brain sentence-level meaning is constructed from words presents a major scientific challenge. Recent advances have begun to explain brain activation elicited by sentences using vector models of word meaning derived ...

Predicting Parkinson's disease trajectory using clinical and neuroimaging baseline measures.

Parkinsonism & related disorders
INTRODUCTION: Predictive biomarkers of Parkinson's Disease progression are needed to expedite neuroprotective treatment development and facilitate prognoses for patients. This work uses measures derived from resting-state functional magnetic resonanc...

Sparse deep neural networks on imaging genetics for schizophrenia case-control classification.

Human brain mapping
Deep learning methods hold strong promise for identifying biomarkers for clinical application. However, current approaches for psychiatric classification or prediction do not allow direct interpretation of original features. In the present study, we ...

Improved cortical surface reconstruction using sub-millimeter resolution MPRAGE by image denoising.

NeuroImage
Automatic cerebral cortical surface reconstruction is a useful tool for cortical anatomy quantification, analysis and visualization. Recently, the Human Connectome Project and several studies have shown the advantages of using T-weighted magnetic res...

Deep reasoning neural network analysis to predict language deficits from psychometry-driven DWI connectome of young children with persistent language concerns.

Human brain mapping
This study investigated whether current state-of-the-art deep reasoning network analysis on psychometry-driven diffusion tractography connectome can accurately predict expressive and receptive language scores in a cohort of young children with persis...

Automatic recognition of specific local cortical folding patterns.

NeuroImage
The study of local cortical folding patterns showed links with psychiatric illnesses as well as cognitive functions. Despite the tools now available to visualize cortical folds in 3D, manually classifying local sulcal patterns is a time-consuming and...

coupleCoC+: An information-theoretic co-clustering-based transfer learning framework for the integrative analysis of single-cell genomic data.

PLoS computational biology
Technological advances have enabled us to profile multiple molecular layers at unprecedented single-cell resolution and the available datasets from multiple samples or domains are growing. These datasets, including scRNA-seq data, scATAC-seq data and...

The neural representation of abstract words may arise through grounding word meaning in language itself.

Human brain mapping
In order to describe how humans represent meaning in the brain, one must be able to account for not just concrete words but, critically, also abstract words, which lack a physical referent. Hebbian formalism and optimization are basic principles of b...

Adaptive Dropout Method Based on Biological Principles.

IEEE transactions on neural networks and learning systems
Dropout is one of the most widely used methods to avoid overfitting neural networks. However, it rigidly and randomly activates neurons according to a fixed probability, which is not consistent with the activation mode of neurons in the human cerebra...