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Cholesterol, HDL

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Apolipoprotein A-I: A favorable prognostic marker in infective endocarditis.

Journal of clinical lipidology
BACKGROUND: Decreased apolipoprotein A-I (apoA-I) and high-density lipoprotein cholesterol (HDL-C) are common in inflammation and sepsis. No study with a large sample size has been performed to investigate the prognostic value of apoA-I or HDL-C in i...

Melatonin administration lowers biomarkers of oxidative stress and cardio-metabolic risk in type 2 diabetic patients with coronary heart disease: A randomized, double-blind, placebo-controlled trial.

Clinical nutrition (Edinburgh, Scotland)
BACKGROUND & AIMS: Melatonin may benefit diabetic people with coronary heart disease (CHD) through its beneficial effects on biomarkers of oxidative stress and cardio-metabolic risk. This investigation evaluated the effects of melatonin administratio...

Inflammatory markers modify the risk of recurrent coronary events associated with apolipoprotein A-I in postinfarction patients.

Journal of clinical lipidology
BACKGROUND: Laboratory findings have suggested that systemic and vascular inflammation can impair the antiatherogenic function of high-density lipoproteins (HDLs). However, evidence from population studies is sparse.

Prediction of Incident Diabetes in the Jackson Heart Study Using High-Dimensional Machine Learning.

PloS one
Statistical models to predict incident diabetes are often based on limited variables. Here we pursued two main goals: 1) investigate the relative performance of a machine learning method such as Random Forests (RF) for detecting incident diabetes in ...