AIMC Topic: Cholesterol

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Screening biomarkers related to cholesterol metabolism in osteoarthritis based on transcriptomics.

Scientific reports
Cholesterol metabolism-related genes (CMRGs) have been associated with osteoarthritis (OA), but their specific regulatory mechanisms remain unclear. This study aimed to investigate the role of CMRGs in OA and provide new insights into its treatment. ...

Establishing a preoperative predictive model for gallbladder adenoma and cholesterol polyps based on machine learning: a multicentre retrospective study.

World journal of surgical oncology
BACKGROUND: With the rising diagnostic rate of gallbladder polypoid lesions (GPLs), differentiating benign cholesterol polyps from gallbladder adenomas with a higher preoperative malignancy risk is crucial. This study aimed to establish a preoperativ...

Novel design of fractional cholesterol dynamics and drug concentrations model with analysis on machine predictive networks.

Computers in biology and medicine
Within the intricate fabric of human physiology, cholesterol, a lipid present in cell membranes exerts a discernible effect on the concentration of the drug in human body that influence the aspects of drug pharmacokinetics. The objective of this work...

Noninvasive Total Cholesterol Level Measurement Using an E-Nose System and Machine Learning on Exhaled Breath Samples.

ACS sensors
In this paper, the first e-nose system coupled with machine learning algorithm for noninvasive measurement of total cholesterol level based on exhaled air sample was proposed. The study was conducted with the participation of 151 people, from whom a ...

Impact of nutrition-related laboratory tests on mortality of patients who are critically ill using artificial intelligence: A focus on trace elements, vitamins, and cholesterol.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
BACKGROUND: This study aimed to understand the collective impact of trace elements, vitamins, cholesterol, and prealbumin on patient outcomes in the intensive care unit (ICU) using an advanced artificial intelligence (AI) model for mortality predicti...

Deep Learning-Based Kinetic Analysis in Paper-Based Analytical Cartridges Integrated with Field-Effect Transistors.

ACS nano
This study explores the fusion of a field-effect transistor (FET), a paper-based analytical cartridge, and the computational power of deep learning (DL) for quantitative biosensing via kinetic analyses. The FET sensors address the low sensitivity cha...

Machine learning analysis of serum cholesterol's impact on knee osteoarthritis progression.

Scientific reports
The controversy surrounding whether serum total cholesterol is a risk factor for the graded progression of knee osteoarthritis (KOA) has prompted this study to develop an authentic prediction model using a machine learning (ML) algorithm. The objecti...

The value of CT radiomics combined with deep transfer learning in predicting the nature of gallbladder polypoid lesions.

Acta radiologica (Stockholm, Sweden : 1987)
BACKGROUND: Computed tomography (CT) radiomics combined with deep transfer learning was used to identify cholesterol and adenomatous gallbladder polyps that have not been well evaluated before surgery.

Improved detection of cholesterol gallstones using quasi-material decomposition images generated from single-energy computed tomography images via deep learning.

Radiological physics and technology
In this study, we developed a method for generating quasi-material decomposition (quasi-MD) images from single-energy computed tomography (SECT) images using a deep convolutional neural network (DCNN). Our aim was to improve the detection of choleste...

Incorporating longitudinal history of risk factors into atherosclerotic cardiovascular disease risk prediction using deep learning.

Scientific reports
It is increasingly clear that longitudinal risk factor levels and trajectories are related to risk for atherosclerotic cardiovascular disease (ASCVD) above and beyond single measures. Currently used in clinical care, the Pooled Cohort Equations (PCE)...