AIMC Topic: Computational Biology

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A knowledge base for Vitis vinifera functional analysis.

BMC systems biology
BACKGROUND: Vitis vinifera (Grapevine) is the most important fruit species in the modern world. Wine and table grapes sales contribute significantly to the economy of major wine producing countries. The most relevant goals in wine production concern ...

Toward Synthesizing Our Knowledge of Morphology: Using Ontologies and Machine Reasoning to Extract Presence/Absence Evolutionary Phenotypes across Studies.

Systematic biology
The reality of larger and larger molecular databases and the need to integrate data scalably have presented a major challenge for the use of phenotypic data. Morphology is currently primarily described in discrete publications, entrenched in noncompu...

Identification of Mitral Annulus Hinge Point Based on Local Context Feature and Additive SVM Classifier.

Computational and mathematical methods in medicine
The position of the hinge point of mitral annulus (MA) is important for segmentation, modeling and multimodalities registration of cardiac structures. The main difficulties in identifying the hinge point of MA are the inherent noisy, low resolution o...

Developing an Intelligent Automatic Appendix Extraction Method from Ultrasonography Based on Fuzzy ART and Image Processing.

Computational and mathematical methods in medicine
Ultrasound examination (US) does a key role in the diagnosis and management of the patients with clinically suspected appendicitis which is the most common abdominal surgical emergency. Among the various sonographic findings of appendicitis, outer di...

Methods for discovery and characterization of cell subsets in high dimensional mass cytometry data.

Methods (San Diego, Calif.)
The flood of high-dimensional data resulting from mass cytometry experiments that measure more than 40 features of individual cells has stimulated creation of new single cell computational biology tools. These tools draw on advances in the field of m...

The SwissLipids knowledgebase for lipid biology.

Bioinformatics (Oxford, England)
MOTIVATION: Lipids are a large and diverse group of biological molecules with roles in membrane formation, energy storage and signaling. Cellular lipidomes may contain tens of thousands of structures, a staggering degree of complexity whose significa...

Diagnostic Accuracy Comparison of Artificial Immune Algorithms for Primary Headaches.

Computational and mathematical methods in medicine
The present study evaluated the diagnostic accuracy of immune system algorithms with the aim of classifying the primary types of headache that are not related to any organic etiology. They are divided into four types: migraine, tension, cluster, and ...

Community challenges in biomedical text mining over 10 years: success, failure and the future.

Briefings in bioinformatics
One effective way to improve the state of the art is through competitions. Following the success of the Critical Assessment of protein Structure Prediction (CASP) in bioinformatics research, a number of challenge evaluations have been organized by th...