AIMC Topic: Creatinine
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Personalized prediction model generated with machine learning for kidney function one year after living kidney donation.
Scientific reports
Jul 1, 2025
Living kidney donors typically experience approximately a 30% reduction in kidney function after donation, although the degree of reduction varies among individuals. This study aimed to develop a machine learning (ML) model to predict serum creatinin...
A negative combined effect of exposure to maternal Mn-Cu-Rb-Fe metal mixtures on gestational anemia, and the mediating role of creatinine in the Guangxi Birth Cohort Study (GBCS): Twelve machine learning algorithms.
Ecotoxicology and environmental safety
May 31, 2025
The link between individual metals and gestational anemia has been established, but the impact of metal mixtures and the mediating role of renal function on gestational anemia remain inconclusive. The concentrations of 20 blood essential trace and no...
Development and validation of multi-center serum creatinine-based models for noninvasive prediction of kidney fibrosis in chronic kidney disease.
Renal failure
Apr 15, 2025
OBJECTIVE: Kidney fibrosis is a key pathological feature in the progression of chronic kidney disease (CKD), traditionally diagnosed through invasive kidney biopsy. This study aimed to develop and validate a noninvasive, multi-center predictive model...
A comparison of neural networks and regression-based approaches for estimating kidney function in pediatric chronic kidney disease: Practical predictive epidemiology for clinical management of a progressive disease.
Annals of epidemiology
Apr 8, 2025
PURPOSE: Clinical management of pediatric chronic kidney disease requires estimation of glomerular filtration rate (eGFR). Currently, eGFR is determined by two endogenous markers measured in blood: serum creatine (SCr) and cystatin C (CysC). Machine ...
Machine learning algorithms for diabetic kidney disease risk predictive model of Chinese patients with type 2 diabetes mellitus.
Renal failure
Apr 7, 2025
BACKGROUND: Diabetic kidney disease (DKD) is a common and serious complication of diabetic mellitus (DM). More sensitive methods for early DKD prediction are urgently needed. This study aimed to set up DKD risk prediction models based on machine lear...
Risk prediction for acute kidney disease and adverse outcomes in patients with chronic obstructive pulmonary disease: an interpretable machine learning approach.
Renal failure
Apr 7, 2025
BACKGROUND: Little is known about acute kidney injury (AKI) and acute kidney disease (AKD) in patients with chronic obstructive pulmonary disease (COPD) and COPD mortality based on the acute/subacute renal injury. This study develops machine learning...
A neural network approach to glomerular filtration rate estimation: a single-centre retrospective audit.
Nuclear medicine communications
Apr 7, 2025
OBJECTIVES: The 2009 Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation without race correction factor is frequently used for an estimate of glomerular filtration rate (eGFR) and to support a single-sample GFR regime. This study exa...
Machine Learning to Assist in Managing Acute Kidney Injury in General Wards: Multicenter Retrospective Study.
Journal of medical Internet research
Mar 18, 2025
BACKGROUND: Most artificial intelligence-based research on acute kidney injury (AKI) prediction has focused on intensive care unit settings, limiting their generalizability to general wards. The lack of standardized AKI definitions and reliance on in...
Estimation of Ganciclovir Exposure in Adults Transplant Patients by Machine Learning.
The AAPS journal
Feb 28, 2025
INTRODUCTION: Valganciclovir, a prodrug of ganciclovir (GCV), is used to prevent cytomegalovirus infection after transplantation, with doses adjusted based on creatinine clearance (CrCL) to target GCV AUC0-24 h of 40-60 mg*h/L. This sometimes leads t...
Prediction of contrast-associated acute kidney injury with machine-learning in patients undergoing contrast-enhanced computed tomography in emergency department.
Scientific reports
Feb 27, 2025
Radiocontrast media is a major cause of nephrotoxic acute kidney injury(AKI). Contrast-enhanced CT(CE-CT) is commonly performed in emergency departments(ED). Predicting individualized risks of contrast-associated AKI(CA-AKI) in ED patients is challen...
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