BACKGROUND: Low back pain resulting from intervertebral disc degeneration (IVDD) represents a significant global social problem. There are notable differences in the distribution of lymphatic vessels (LV) in normal and pathological intervertebral dis...
Age-related macular degeneration is a retinal disease that severely impacts vision in the older population. Its gene-related heterogeneity has not been fully studied, increasing the burden of precise treatment, prevention and prognosis. Genetic varia...
PURPOSE: Mitochondria are involved in septic shock and inflammatory response syndrome, which severely affects the life security of patients. It is necessary to recognize and explore the immune-mitochondrial genes in septic shock.
The increasing availability of massive genetic sequencing data in the clinical setting has triggered the need for appropriate tools to help fully exploit the wealth of information these data possess. GFPrint™ is a proprietary streaming algorithm desi...
The Explainable Modular Neural Network (XModNN) enables the identification of biomarkers, facilitating the classification of diseases and clinical parameters in transcriptomic datasets. The modules within XModNN represent specific pathways or genes o...
Heart failure (HF) threatens tens of millions of people's health worldwide, which is the terminal stage in the development of majority cardiovascular diseases. Recently, an increasing number of studies have demonstrated that bioinformatics and machin...
BACKGROUND: We aimed to identify the potential diagnostic markers and associated molecular mechanisms based on programmed cell death (PCD)-related genes in patients with heart failure (HF).
Anoikis-related genes (ANRGs) are crucial in the invasion and metastasis of breast cancer (BC). The underlying role of ANRGs in the prognosis of breast cancer patients warrants further study. The anoikis-related prognostic signature (ANRS) was gene...
Medical science monitor : international medical journal of experimental and clinical research
Nov 6, 2024
BACKGROUND Peri-implantitis is the main cause of failure of implant treatment, and there is little research on its molecular mechanism. This study aimed to identify key biomarkers and immune infiltration of peri-implantitis using a bioinformatics met...
IEEE journal of biomedical and health informatics
Nov 6, 2024
Gene expression data can serve for analyzing the genes with changed expressions, the correlation between genes and the influence of different circumstance on gene activities. However, labeling a large number of gene expression data is laborious and t...
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