Current care in multiple sclerosis (MS) primarily relies on infrequently obtained data such as magnetic resonance imaging, clinical laboratory tests or clinical history, resulting in subtle changes that may occur between visits being missed. Mobile t...
BACKGROUND: Esophageal cancer is the sixth most common cancer worldwide, with a high mortality rate. Early prognosis of esophageal abnormalities can improve patient survival rates. The progression of esophageal cancer follows a sequence from esophagi...
BACKGROUND: To develop a predictive model for bone destruction in patients with rheumatoid arthritis (RA), based on the characteristics of plasma metabolites and common clinical indicators.
Friedreich ataxia (FRDA) is a rare, inherited progressive movement disorder for which there is currently no cure. The field urgently requires more sensitive, objective, and clinically relevant biomarkers to enhance the evaluation of treatment efficac...
Accurate differentiation of pseudoprogression (PsP) from True Progression (TP) following radiotherapy (RT) in glioblastoma patients is crucial for optimal treatment planning. However, this task remains challenging due to the overlapping imaging chara...
International journal of molecular sciences
May 15, 2025
Osteoarthritis (OA) is a prevalent and disabling chronic disease, with knee OA being the most common form, affecting approximately 73% of individuals over 55 years. Traditional clinical assessments often fail to predict knee structural progression ac...
International journal of molecular sciences
May 15, 2025
Glaucoma is an age-related neurodegenerative disease characterized by progressive optic nerve damage. Accelerated biological aging, assessed using predicted age derived from fundus images, may serve as a biomarker for glaucoma progression. This study...
Studies in health technology and informatics
May 15, 2025
Recently, machine learning methods have emerged to predict dental disease progression, often relying on costly annotated datasets and frequently exhibiting low generalization performance. This study evaluates the application of Siamese networks for d...
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common and progressive respiratory condition characterized by persistent airflow limitation and symptoms such as dyspnea, cough, and sputum production. Acute exacerbations (AE) of COPD (AE...
BACKGROUND: Progression-free survival (PFS) is a crucial endpoint in cancer drug research. Clinician-confirmed cancer progression, namely real-world PFS (rwPFS) in unstructured text (ie, clinical notes), serves as a reasonable surrogate for real-worl...
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