BACKGROUND: Autoantibodies represent promising diagnostic blood-based biomarkers that may be generated prior to the first clinically detectable signs of cancers. In present study, we aimed to identify a novel optimized autoantibody panel with high di...
International journal of molecular sciences
Apr 18, 2025
Hepatocellular carcinoma (HCC) is a major complication of tyrosinemia type 1 (HT-1), an inborn error of metabolism affecting tyrosine catabolism. The risk of HCC is higher in late diagnoses despite treatment. Alpha-fetoprotein (AFP) is widely used to...
BACKGROUND: Endometrial cancer is one of the most common gynecological tumors, and early screening and diagnosis are crucial for its treatment. Research on the application of artificial intelligence (AI) in the diagnosis of endometrial cancer is incr...
Critical reviews in oncology/hematology
Apr 17, 2025
The rising number of cervical cancer cases is placing a heavy economic strain on the country and its people. Improving survival rates hinges on early detection, precise diagnosis, and thorough treatment. Common screening and diagnostic methods like P...
Deep learning (DL) models for medical image analysis are majorly bottlenecked by the lack of well-annotated datasets. Bronchoalveolar lavage (BAL) is a minimally invasive procedure to diagnose lung cancer, but BAL cytology suffers from low sensitivit...
BACKGROUND: Cancer remains a significant health challenge in the ASEAN region, highlighting the need for effective screening programs. However, approaches, target demographics, and intervals vary across ASEAN member states, necessitating a comprehens...
Breast cancer ranks among the most prevalent cancers in women globally, with its treatment efficacy heavily reliant on the early identification and diagnosis of the disease. The importance of early detection and diagnosis cannot be overstated in enha...
BACKGROUND: In recent years, significant progress has been made in the treatment of nasopharyngeal carcinoma (NPC). The application of immunotherapy, especially the use of Programmed Cell Death Protein 1 inhibitors, has demonstrated excellent therape...
Lung cancer, which claims 1.8 million lives annually, is still one of the leading causes of cancer-related deaths globally. Patients with lung cancer frequently have a bad prognosis because of late-stage detection, which severely limits treatment opt...
Deep learning (DL) enabled liquid-based cytology has potential for cervical cancer screening or triage. Here, we develop a DL model using whole cytology slides from 17,397 women and test it on 10,826 additional cases through a three-stage process. Th...
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