AIMC Topic: Early Diagnosis

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Cell death-related gene signatures as dual-function biomarkers: Early diagnosis and therapeutic targeting in Staphylococcus aureus pneumonia.

PloS one
BACKGROUND: Staphylococcus aureus (S. aureus) pneumonia constitutes a lethal respiratory infection with persistently high clinical mortality. Although programmed cell death (PCD) pathways are implicated in diverse disease processes, their mechanistic...

Dynamic Ensemble Selection for Early Detection of Deep Vein Thrombosis in Fracture Patients.

Journal of medical systems
Deep vein thrombosis (DVT) in fracture patients is often clinically silent, with a high incidence of thrombosis and associated mortality. Static machine learning methods struggle to address the challenge of early DVT diagnosis due to their inability ...

Early diagnostic biomarkers for acute myocardial infarction unveiled by metabolomics, Mendelian randomization, and machine learning.

Molecular biomedicine
Acute myocardial infarction (AMI) remains a leading cause of global cardiovascular morbidity and mortality. Limitations in current diagnostic methods hinder early detection and intervention, creating an urgent need for novel early diagnostic biomarke...

Integrative multi-omics and network-based machine learning for early diagnosis of Parkinson's disease.

PloS one
BACKGROUND: Accurate diagnosis of Parkinson's Disease (PD) remains challenging due to its biological complexity. Integrating machine learning with multi-omics and network topological analyses may enhance diagnostic precision.

Construction of an early diagnostic model for pulmonary hypertension based on aging-related signature genes and identification of potential therapeutic targets.

Scientific reports
Pulmonary hypertension (PH) is a progressive cardiopulmonary disorder. It features elevated pulmonary arterial pressure, which leads to right ventricular failure and increased mortality. PH's insidious nature, with no specific clinical symptoms, hind...

Early detection of paroxysmal atrial fibrillation from non-episodic ECG data using cardiac dynamics features and different classification models.

Biomedical physics & engineering express
Intelligent computer-aided diagnosis techniques enable inspection of invisible electrocardiogram (ECG) pathological changes for early detection of latent heart diseases. This study concentrates on latent pathological changes within non-episodic ECG d...

Development and validation of a screening model for early diagnosis of biliary atresia in neonates with cholestasis.

Pediatric surgery international
BACKGROUND: Biliary atresia (BA) is a progressive neonatal cholestatic liver disease that requires timely diagnosis and intervention. Differentiating BA from other causes of neonatal cholestasis remains a significant clinical challenge.

Deep neural networks and deep deterministic policy gradient for early ASD diagnosis and personalized intervention in children.

Scientific reports
Early diagnosis and personalized intervention for Autism Spectrum Disorder (ASD) in children can potentially improve developmental outcomes, though current methods often lack scalability and adaptability. This study introduces an integrated system co...

Early diagnosis of transient ischemic attack facilitated by SERS-based artificial intelligence sensors.

Mikrochimica acta
Transient ischemic attack (TIA) serves as a critical early warning sign for ischemic stroke. Its timely identification holds significant clinical value in reducing recurrence risk and improving patient prognosis. However, existing detection methods e...

Earlier prediction of Parkinson's disease using cross non-decimated wavelet transform and machine learning algorithm.

Scientific reports
Parkinson's disease (PD) is a brain disorder, that affects a person's body movement causing stiffness, shaking and imbalance. Earlier detection of PD is a challenging task for researchers. In this paper, earlier detection of PD is performed using the...