AIMC Topic: Electrophysiological Phenomena

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Using deep neural networks to detect complex spikes of cerebellar Purkinje cells.

Journal of neurophysiology
One of the most powerful excitatory synapses in the brain is formed by cerebellar climbing fibers, originating from neurons in the inferior olive, that wrap around the proximal dendrites of cerebellar Purkinje cells. The activation of a single olivar...

Dynamics of unidirectionally-coupled ring neural network with discrete and distributed delays.

Journal of mathematical biology
In this paper, we consider a ring neural network with one-way distributed-delay coupling between the neurons and a discrete delayed self-feedback. In the general case of the distribution kernels, we are able to find a subset of the amplitude death re...

Multiclass Classification of Hepatic Anomalies with Dielectric Properties: From Phantom Materials to Rat Hepatic Tissues.

Sensors (Basel, Switzerland)
Open-ended coaxial probes can be used as tissue characterization devices. However, the technique suffers from a high error rate. To improve this technology, there is a need to decrease the measurement error which is reported to be more than 30% for a...

Endocannabinoid degradation inhibitors ameliorate neuronal and synaptic alterations following traumatic brain injury.

Journal of neurophysiology
Our previous work showed that lateral fluid percussion injury to the sensorimotor cortex (SMC) of anesthetized rats increased neuronal synaptic hyperexcitability in layer 5 (L5) neurons in ex vivo brain slices 10 days postinjury. Furthermore, endocan...

Deep-Channel uses deep neural networks to detect single-molecule events from patch-clamp data.

Communications biology
Single-molecule research techniques such as patch-clamp electrophysiology deliver unique biological insight by capturing the movement of individual proteins in real time, unobscured by whole-cell ensemble averaging. The critical first step in analysi...

A mean-field approach to the dynamics of networks of complex neurons, from nonlinear Integrate-and-Fire to Hodgkin-Huxley models.

Journal of neurophysiology
We present a mean-field formalism able to predict the collective dynamics of large networks of conductance-based interacting spiking neurons. We apply this formalism to several neuronal models, from the simplest Adaptive Exponential Integrate-and-Fir...

Electrophysiological assessment of plant status outside a Faraday cage using supervised machine learning.

Scientific reports
Living organisms have evolved complex signaling networks to drive appropriate physiological processes in response to changing environmental conditions. Amongst them, electric signals are a universal method to rapidly transmit information. In animals,...

A dictionary learning approach for spatio-temporal characterization of absence seizures.

Physiological measurement
OBJECTIVE: This research explores absence seizures using data recorded from different layers of somatosensory cortex of four genetic absence epilepsy rats from Strasbourg (GAERS). Localizing the active layers of somatosensory cortex (spatial analysis...

A comprehensive knowledge base of synaptic electrophysiology in the rodent hippocampal formation.

Hippocampus
The cellular and synaptic architecture of the rodent hippocampus has been described in thousands of peer-reviewed publications. However, no human- or machine-readable public catalog of synaptic electrophysiology data exists for this or any other neur...